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IL-6R (Tocilizumab Biosimilar) Antibodies

(IL-6R (Tocilizumab Biosimilar))
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011].

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Recommended IL-6R (Tocilizumab Biosimilar) Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, InhA
Validations
  • (1)
Cat. No. ABIN5668254
Quantity 200 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, InhA
Validations
  • (1)
Cat. No. ABIN5668253
Quantity 200 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS
Validations
Cat. No. ABIN7093060
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our IL-6R (Tocilizumab Biosimilar) products

Hsieh, Hsu, Chang, Lai: "IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells." in: Nature communications, Vol. 9, Issue 1, pp. 463, (2018) (PubMed).

Synonyms and alternative names related to IL-6R (Tocilizumab Biosimilar)

interleukin 6 receptor (IL6R), CD126, gp80, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ

Protein level used designations for IL-6R (Tocilizumab Biosimilar)

  • CD126 antigen
  • IL-6 receptor subunit alpha
  • IL-6R 1
  • interleukin-6 receptor subunit alpha
  • membrane glycoprotein 80
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