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IL27 Receptor alpha Products

(Interleukin 27 Receptor, alpha (IL27RA))
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. [provided by RefSeq, Jul 2008].

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Featured IL27 Receptor alpha Categories

IL27 Receptor alpha Antibodies

High quality antibodies with extensive validation data.

IL27 Receptor alpha ELISA Kits

Reliable ELISA kits for a wide range of species.

IL27 Receptor alpha Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IL27 Receptor alpha Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro)
Validations
  • (1)
  • (4)
Cat. No. ABIN749498
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7156877
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7444133
Quantity 100 μL
Datasheet Datasheet

Recommended IL27 Receptor alpha ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4883399
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6384792
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730225
Quantity 96 tests
Datasheet Datasheet

Recommended IL27 Receptor alpha Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275016
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275033
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307804
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our IL27 Receptor alpha products

Xu, Yi, Wang, Hu, Han, Xue, Zhang, Luan: "IL-27 regulates the adherence, proliferation, and migration of MSCs and enhances their regulatory effects on Th1 and Th2 subset generations." in: Immunologic research, Vol. 65, Issue 4, pp. 903-912, (2017) (PubMed).

Vijayan, Mohd Redzwan, Avery, Wirasinha, Brink, Walters, Adelstein, Kobayashi, Gray, Elliott, Wong, King, Vinuesa, Ghilardi, Ma, Tangye, Batten: "IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 8, pp. 3008-3017, (2016) (PubMed).

Di Carlo, Sorrentino, Zorzoli, Di Meo, Tupone, Ognio, Mincione, Airoldi: "The antitumor potential of Interleukin-27 in prostate cancer." in: Oncotarget, Vol. 5, Issue 21, pp. 10332-41, (2015) (PubMed).

Morandi, Di Carlo, Ferrone, Petretto, Pistoia, Airoldi: "IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 6, pp. 2634-42, (2014) (PubMed).

Mascanfroni, Yeste, Vieira, Burns, Patel, Sloma, Wu, Mayo, Ben-Hamo, Efroni, Kuchroo, Robson, Quintana: "IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39." in: Nature immunology, Vol. 14, Issue 10, pp. 1054-63, (2013) (PubMed).

Kachroo, Lee, Zhang, Baratelli, Lee, Srivastava, Wang, Walser, Krysan, Sharma, Dubinett, Lee: "IL-27 inhibits epithelial-mesenchymal transition and angiogenic factor production in a STAT1-dominant pathway in human non-small cell lung cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 32, pp. 97, (2013) (PubMed).

Tzeng, Tsay, Chang, Hsu, Lai, Huang, Shiao: "Caspase 3 involves in neuroplasticity, microglial activation and neurogenesis in the mice hippocampus after intracerebral injection of kainic acid." in: Journal of biomedical science, Vol. 20, pp. 90, (2013) (PubMed).

Guzzo, Hopman, Che Mat, Wobeser, Gee: "IL-27-induced gene expression is downregulated in HIV-infected subjects." in: PLoS ONE, Vol. 7, Issue 9, pp. e45706, (2012) (PubMed).

Cocco, Di Carlo, Zupo, Canale, Zorzoli, Ribatti, Morandi, Ognio, Airoldi: "Complementary IL-23 and IL-27 anti-tumor activities cause strong inhibition of human follicular and diffuse large B-cell lymphoma growth in vivo." in: Leukemia, Vol. 26, Issue 6, pp. 1365-74, (2012) (PubMed).

Pradhan, Lambert, Reuther: "Transformation of hematopoietic cells and activation of JAK2-V617F by IL-27R, a component of a heterodimeric type I cytokine receptor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 47, pp. 18502-7, (2007) (PubMed).

Synonyms and alternative names related to IL27 Receptor alpha

interleukin 27 receptor subunit alpha (IL27RA), interleukin-27 receptor subunit alpha (LOC484907), interleukin 27 receptor, alpha (Il27ra), interleukin 27 receptor subunit alpha (Il27ra), CRL1, IL-27R, IL-27RA, IL27R, IL27RA, TCCR, Tccr, WSX-1, WSX1, Wsx1, zcytor1

Protein level used designations for IL27 Receptor alpha

  • interleukin 27 receptor, alpha
  • class I cytokine receptor
  • interleukin-27 receptor subunit alpha
  • type-I T cell cytokine receptor
  • IL-27 receptor subunit alpha
  • IL-27R subunit alpha
  • IL-27R-alpha
  • T-cell cytokine receptor type 1
  • cytokine receptor WSX-1
  • cytokine receptor-like 1
  • type I T-cell cytokine receptor
  • IL-27RA
  • T cell cytokine receptor
  • T cell cytokine receptor; cytokine receptor family, class 1 (WSXWS), member 1
  • cytokine receptor family, class 1 (WSXWS), member 1
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