Integrin beta 2 Protein (ITGB2) (AA 23-700) (His tag)
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- Target See all Integrin beta 2 (ITGB2) Proteins
- Integrin beta 2 (ITGB2)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-700
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This Integrin beta 2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- QECTKFKVSS CRECIESGPG CTWCQKLNFT GPGDPDSIRC DTRPQLLMRG CAADDIMDPT SLAETQEDHN GGQKQLSPQK VTLYLRPGQA AAFNVTFRRA KGYPIDLYYL MDLSYSMLDD LRNVKKLGGD LLRALNEITE SGRIGFGSFV DKTVLPFVNT HPDKLRNPCP NKEKECQPPF AFRHVLKLTN NSNQFQTEVG KQLISGNLDA PEGGLDAMMQ VAACPEEIGW RNVTRLLVFA TDDGFHFAGD GKLGAILTPN DGRCHLEDNL YKRSNEFDYP SVGQLAHKLA ENNIQPIFAV TSRMVKTYEK LTEIIPKSAV GELSEDSSNV VQLIKNAYNK LSSRVFLDHN ALPDTLKVTY DSFCSNGVTH RNQPRGDCDG VQINVPITFQ VKVTATECIQ EQSFVIRALG FTDIVTVQVL PQCECRCRDQ SRDRSLCHGK GFLECGICRC DTGYIGKNCE CQTQGRSSQE LEGSCRKDNN SIICSGLGDC VCGQCLCHTS DVPGKLIYGQ YCECDTINCE RYNGQVCGGP GRGLCFCGKC RCHPGFEGSA CQCERTTEGC LNPRRVECSG RGRCRCNVCE CHSGYQLPLC QECPGCPSPC GKYISCAECL KFEKGPFGKN CSAACPGLQL SNNPVKGRTC KERDSEGCWV AYTLEQQDGM DRYLIYVDES RECVAGPNLE HHHHHH
- Purity
- > 85 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product ITGB2 Protein
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Integrin beta 2 (ITGB2) (AA 1-769) protein (GST tag)
ITGB2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Integrin beta 2 (ITGB2) (AA 600-699) protein (GST tag)ITGB2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Integrin beta 2 (ITGB2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)ITGB2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Integrin beta 2 (ITGB2)
- Alternative Name
- ITGB2 (ITGB2 Products)
- Synonyms
- CD18 Protein, LAD Protein, LCAMB Protein, LFA-1 Protein, MAC-1 Protein, MF17 Protein, MFI7 Protein, 2E6 Protein, AI528527 Protein, Cd18 Protein, Lfa1 Protein, ITGB2 Protein, itgb2 Protein, itgb2-a Protein, itgb2-b Protein, integrin subunit beta 2 Protein, integrin beta 2 Protein, integrin subunit beta 2 S homeolog Protein, ITGB2 Protein, Itgb2 Protein, itgb2.S Protein
- Background
- ITGB2, also known as integrin beta-2, is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It may belong to an extended family of cell surface molecules including the fibronectin binding protein. Also It is a complement receptor type 3 (CR3). It triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. Recombinant human ITGB2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 75.9kDa (686aa) 70-100kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_000202
- Pathways
- NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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