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Clofazimine

InhA, Func 2030-63-9
Catalog No. ABIN4869526
  • Application
    Inhibition Assay (InhA), Functional Studies (Func)
    Purpose
    A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
    Characteristics
    Tradename: LAMPRENE
    Source of Compound: synthetic, NSC-141046, G-30320
    Target: CzcO-like inhibitor,DNA intercalation
    Receptor: CzcO-like,DNA
    Purification
    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
    Purity
    99 %
    Formula
    C27H22Cl2N4
    Solubility
    Water: 0.225 mg/L
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Solid
    Storage
    -20 °C
    Storage Comment
    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
    Expiry Date
    24 months
  • Background
    DNA Damage/DNA Repair,Enzyme
    Molecular Weight
    473.40 g/mol
    CAS-No
    2030-63-9
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