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Triacetylresveratrol

Act 42206-94-0 5-[(1E)-2-[4-(Acetyloxy)phenyl]ethenyl]-1,3-benzenediol-1,3-diacetate
Catalog No. ABIN7233301

Quick Overview for Triacetylresveratrol (ABIN7233301)

Application

Activation (Act)

Chemical Name

5-[(1E)-2-[4-(Acetyloxy)phenyl]ethenyl]-1,3-benzenediol-1,3-diacetate
  • Purpose

    SIRT activator, prodrug

    Characteristics

    A resveratrol prodrug. One method for increasing the half-life of resveratrol in vivo is acetylation of the phenolic OH groups. Deacetylation takes place in vivo or in intact cells via the action of intracellular esterases releasing active resveratrol. CWR22Rv1 cells when exposed to triacetyl resveratrol showed a G1S block concomitant with increased p53 and p21 expression. In MCF-7 cells it induced both ERK and p38 phosphorylation.

    Purity

    >98 %

    Formula

    C20H28O6

    Solubility

    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 8 mg/ml).
  • Restrictions

    For Research Use only
  • Format

    Powder

    Storage

    -20 °C
  • Background

    3,5,4'-Tri-O-acetylresveratrol,NFkappaB,Epigenetics,Apoptosis inducer,Hedgehog,PI3K,Protein deacetylase,Antioxidant,Cell death,Immunology,Cancer,Diabetes,Ageing,Posttranslational modification,Inflammation,Chromatin

    Molecular Weight

    364.4

    CAS-No

    42206-94-0
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