Trichostatin A
Quick Overview for Trichostatin A (ABIN7233302)
Application
Chemical Name
Permeability
-
-
Purpose
- HDAC inhibitor
-
Characteristics
- Potent and selective histone deacetylase (HDAC) inhibitor (Ki = 3.4 nM). Induces reversion of ras transformed cells to normal morphology. Induces dedifferentiation of primordial germ cells into embryonic germ cells. Cell permeable and active in vivo.
-
Purity
- >98 %
-
Formula
- C17H22N2O3
-
Solubility
- Soluble in DMSO (up to 15 mg/ml), or in Ethanol (up to 3 mg/ml).
-
-
Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
5-AzacytidineInh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
NicotinamideInh 98-92-0 Pyridine-3-carboxylic acid amide
SAHA (Vorinostat)Inh Cell-permeable 149647-78-9 Suberoylanilide-hydroxamic acid
Phenylbutyrate NaInh 1716-12-7 4-Phenylbutyric acid, sodium salt
CI-994Inh 112522-64-2 4-(Acetylamino)-N-(2-aminophenyl)benzamide
Tranylcypromine hemisulfate (±)Inh Cell-permeable 13492-01-8 Trans (±)-2-phenylcyclopropanamine, hemisulfate salt
Tenovin-1Inh 380315-80-0 N-[(4-Acetamidophenyl)carbamothioyl]-4-tert-butylbenzamide
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Powder
-
Storage
- -20 °C
-
-
-
Background
- TSA,Apoptosis inducer,Epigenetics,Cell cycle,Protein deacetylase,Stem cells,Cell death,Cancer,Infectious disease,Posttranslational modification,Chromatin
-
Molecular Weight
- 302.38
-
CAS-No
- 58880-19-6
-
-
