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Human Polyclonal MED13 Primary Antibody for IP, WB - ABIN253113
Knuesel, Meyer, Donner, Espinosa, Taatjes: The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator. in Molecular and cellular biology 2009
Show all 2 Pubmed References
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator.
mediator complex subunit 13
, thyroid hormone receptor associated protein 1
, activator-recruited cofactor 250 kDa component
, mediator of RNA polymerase II transcription subunit 13
, mediator of RNA polymerase II transcription, subunit 13 homolog
, thyroid hormone receptor-associated protein 1
, thyroid hormone receptor-associated protein complex 240 kDa component
, thyroid hormone receptor-associated protein complex component TRAP240
, thyroid hormone receptor-associated protein, 240 kDa subunit
, vitamin D3 receptor-interacting protein complex component DRIP250
, Zmediator complex subunit 13
, mediator of RNA polymerase II transcription, subunit 13
, thyroid hormone receptor associated protein, 240 kDa subunit