anti-Rat (Rattus) STAT1 antibody for Immunofluorescence (Cultured Cells)

Recommended STAT1 Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Antibodies
  • CANDF7
  • ISGF-3
  • STAT91
  • 2010005J02Rik
  • AA408197
  • XStat1
  • STAT4
  • DD6G4-4
  • STAT
  • STAT1
  • dZ182H3.3
  • si:by134g18.2
  • si:by51f19.1
  • si:dz182h3.3
  • si:dz199m19.1
  • si:dz73o4.2
  • stat1
  • signal transducer and activator of transcription 1
  • signal transducer and activator of transcription 1 L homeolog
  • signal transducer and activator of transcription 1, 91kDa
  • signal transducer and activator of transcription 4
  • signal transducer and activator of transcription 1a
  • STAT1
  • Stat1
  • stat1.L
  • stat4
  • stat1a
Reactivity
Human, Mouse (Murine), Rat (Rattus)
569
311
255
42
32
27
26
23
18
15
11
10
9
5
4
3
3
2
2
2
2
1
1
Host
Rabbit
432
152
9
3
1
1
Clonality
Monoclonal
Conjugate
This STAT1 antibody is un-conjugated
16
15
12
11
10
10
7
5
5
5
4
4
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunofluorescence (Cultured Cells) (IF (cc)), Western Blotting (WB)
481
226
161
115
103
54
52
29
27
12
9
7
5
5
2
1
1
Options
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Catalog No. ABIN5557529
$ 402.49
Plus shipping costs $45.00

General

Antigen Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(569), (311), (255), (42), (32), (27), (26), (23), (18), (15), (11), (10), (9), (5), (4), (3), (3), (2), (2), (2), (2), (1), (1)
Host Rabbit
(432), (152), (9), (3), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This STAT1 antibody is un-conjugated
(16), (15), (12), (11), (10), (10), (7), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Immunofluorescence (Cultured Cells) (IF (cc)), Western Blotting (WB)
(481), (226), (161), (115), (103), (54), (52), (29), (27), (12), (9), (7), (5), (5), (2), (1), (1)
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Product Details anti-STAT1 Antibody

Target Details STAT1 Application Details Handling Images
Purification Purified by Protein A.
Immunogen Recombinant human STAT1 alpha protein, around C-terminal 100aa.
Clone 2B12
Isotype IgG
Plasmids, Primers & others

Target Details STAT1

Product Details anti-STAT1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name STAT1 alpha (STAT1 Antibody Abstract)
Background

Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. Becomes activated in response to KITLG/SCF and KIT signaling. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.

Synonyms: CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91, Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84, STAT1

Gene ID 6772
UniProt P42224
Pathways JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events

Application Details

Product Details anti-STAT1 Antibody Target Details STAT1 Handling Images back to top
Application Notes WB 1:1000-2000
IF(ICC) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-STAT1 Antibody Target Details STAT1 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-STAT1 Antibody Target Details STAT1 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) antibody (ABIN5557529) Lane 1: Hela, Lane 2: 293 cell lysates probed with STAT1 alpha (2B12) Monoclonal Anti...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) antibody (ABIN5557529) MCF-7 cells were stained with STAT1 alpha (2B12) Monoclonal Antibody at [1:200] incu...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) antibody (ABIN5557529) SKOV-3 cells were stained with STAT1 alpha (2B12) Monoclonal Antibody at [1:200] inc...