JMJD2D Products
(Lysine (K)-Specific Demethylase 4D (KDM4D))
Categories
Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys- 9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate (By similarity).
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Featured JMJD2D Categories
JMJD2D Antibodies
High quality antibodies with extensive validation data.
JMJD2D Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended JMJD2D Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, IHC
Validations
- (3)
Cat. No.
ABIN7002265
Quantity
20 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN6736292
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7158704
Quantity
100 μg
Datasheet
Datasheet
Recommended JMJD2D Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Baculovirus
Validations
- (3)
Cat. No.
ABIN2669707
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308301
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3082371
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our JMJD2D products
: "JMJD2 promotes acquired cisplatin resistance in non-small cell lung carcinoma cells." in: Oncogene, Vol. 38, Issue 28, pp. 5643-5657, (2019) (PubMed).: "Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors." in: American journal of translational research, Vol. 6, Issue 3, pp. 236-47, (2014) (PubMed).
: "Kdm4b histone demethylase is a DNA damage response protein and confers a survival advantage following γ-irradiation." in: The Journal of biological chemistry, Vol. 288, Issue 29, pp. 21376-88, (2013) (PubMed).
: "Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D." in: PLoS ONE, Vol. 7, Issue 4, pp. e34618, (2012) (PubMed).
: "Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 49, pp. E3367-76, (2012) (PubMed).
: "Identification and characterization of JMJD2 family genes in silico." in: International journal of oncology, Vol. 24, Issue 6, pp. 1623-8, (2004) (PubMed).
Synonyms and alternative names related to JMJD2D
lysine demethylase 4D (KDM4D), lysine-specific demethylase 4D (LOC524768), lysine (K)-specific demethylase 4D (Kdm4d), lysine-specific demethylase 4D (LOC617971), lysine-specific demethylase 4D (LOC100067461), lysine demethylase 4D (Kdm4d), lysine-specific demethylase 4D (LOC698455), lysine (K)-specific demethylase 4D (KDM4D), lysine-specific demethylase 4D (LOC100514356), 4932416A15, JMJD2D, Jmjd2d, KDM4DProtein level used designations for JMJD2D
- jmjC domain-containing histone demethylation protein 3D
- jumonji domain containing 2D
- jumonji domain-containing protein 2D
- lysine-specific demethylase 4D
- lysine (K)-specific demethylase 4D
- lysine-specific demethylase 4D-like
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