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KCNN3 Products

(Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))

Categories

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].

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Featured KCNN3 Categories

KCNN3 Antibodies

High quality antibodies with extensive validation data.

KCNN3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KCNN3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (7)
Cat. No. ABIN2776146
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN561588
Quantity 50 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Guinea Pig, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN6736410
Quantity 100 μL
Datasheet Datasheet

Recommended KCNN3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6228987
Quantity 96 tests
Datasheet Datasheet

Recommended KCNN3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308473
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308475
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3120574
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our KCNN3 products

Coyle, ODonnell, Puri: "Altered distribution of small-conductance calcium-activated potassium channel SK3 in Hirschsprung's disease." in: Journal of pediatric surgery, Vol. 50, Issue 10, pp. 1659-64, (2015) (PubMed).

Synonyms and alternative names related to KCNN3

potassium calcium-activated channel subfamily N member 3 (Kcnn3), potassium calcium-activated channel subfamily N member 3 (KCNN3), potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 (Kcnn3), hSK3, KCa2.3, SK3, SKCA3

Protein level used designations for KCNN3

  • SKCa 3
  • SKCa3
  • small conductance calcium-activated potassium channel protein 3
  • small-conductance Ca2+-activated K+ channel 3
  • SK3
  • calcium activated potassium channel SK3
  • small conductance calcium-activated potassium channel 3
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