AOC3 ELISA Kit
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- Target See all AOC3 ELISA Kits
- AOC3 (Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3))
- Binding Specificity
- AA 2-763
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Reactivity
- Human
- Detection Method
- Colorimetric
- Method Type
- Sandwich ELISA
- Detection Range
- 0.78 ng/mL - 50 ng/mL
- Minimum Detection Limit
- 0.78 ng/mL
- Application
- ELISA
- Purpose
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human VAP-1/AOC3. 96wells/kit, with removable strips.
- Brand
- PicoKine™
- Sample Type
- Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
- Analytical Method
- Quantitative
- Specificity
- Expression system for standard: sf21, Immunogen sequence: N2-N763
- Sensitivity
- < 20 pg/mL
- Components
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96-well plate precoated with antibody
lyophilized recombinant standard
biotinylated antibody (dilution 1:100)
Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
Sample diluent buffer
Antibody diluent buffer
ABC diluent buffer
TMB color developing agent
TMB stop solution
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- Assay Time
- 15 min
- Plate
- Pre-coated
- Restrictions
- For Research Use only
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- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- Expiry Date
- 12 months
-
- Target See all AOC3 ELISA Kits
- AOC3 (Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3))
- Alternative Name
- AOC3 (AOC3 Products)
- Synonyms
- HPAO ELISA Kit, SSAO ELISA Kit, VAP-1 ELISA Kit, VAP1 ELISA Kit, aoc2 ELISA Kit, BOLAO ELISA Kit, amine oxidase, copper containing 3 ELISA Kit, amine oxidase, copper containing 3 L homeolog ELISA Kit, AOC3 ELISA Kit, aoc3.L ELISA Kit, Aoc3 ELISA Kit
- Background
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Synonyms: Membrane primary amine oxidase
Tissue Specificity: Strongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis. Isoform 2 seems to be the predominant transcript in fetal kidneys, fetal cartilage and fetal tonsils. The highest relative expression of isoform 2 occurs in skeletal muscle, heart, pancreas, kidney, and lung.
Background: Amine oxidase, copper containing 3, also known as vascular adhesion protein (VAP-1) and HPAO is an enzyme that in humans is encoded by the AOC3 gene on chromosome 17. This protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family and is associated with many vascular diseases. This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants.
Cellular Localisation: Cell membrane - UniProt
- Q16853
- Pathways
- Feeding Behaviour
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