IL-8 ELISA Kit

Catalog No. ABIN577068

The Human IL-8 ELISA Kit (ABIN577068) is a Colorimetric ELISA Kit designed to quantify Human IL-8.

Quick Overview for IL-8 ELISA Kit (ABIN577068)

Target: IL-8 (IL8) (Interleukin 8 (IL8))

Reactivity: Human

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Detection Range: 10-1600 pg/mL

Application: ELISA

Product Details IL-8 ELISA Kit

Minimum Detection Limit: 10 pg/mL

Purpose: For the Quantitative Determination of Human Interleukin-8 (IL-8) Concentrations in Serum, Plasma, Cell Culture Supernatant, and Other Biological Fluids

Analytical Method: Quantitative

Sensitivity: < 10 pg/mL

Components: Standards: 1 set/2 vials

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Preservative: Without preservative

Target Details for IL-8

Target: IL-8 (IL8) (Interleukin 8 (IL8))

Alternative Name: Interleukin-8 (IL-8)

Background: Hepatitis resulting from infection with viruses other than Hepatitis A Virus (HAV) and Hepatitis B (HBV) virus was previously referred to as non-A, non-B hepatitis. The first characterised non-A, non-B hepatitis agent was that responsible for parentally transmitted non-A, non-B hepatitis, or what is now called Hepatitis C Virus. This was followed by the cloning of a portion of the fecal-orally-transmitted agent, the Hepatitis E Virus (HEV). Hepatitis E Virus has been referred to as enterically transmitted non-A, non-B hepatitis. Epidemics of enterically transmitted Hepatitis E Virus have been recognised worldwide but occur principally in developing countries. They have been reported in Southeast Asia, central Asia, Africa, Mexico, and Central America. In these areas, contaminated water has been implicated as the principal vehicle of virus transmission. Although HEV and HAV are transmitted in a similar manner, there are major differences in the clinical, pathological, and epidemiological courses of these two viruses. In particular, the mortality rate for HEV infection is 1 to 2%, or approximately 1-fold greater than that seen for HAV. Infection with HEV is particularly fatal for pregnant women, for whom the mortality rate can be as high as 1 to 2%. This HEV IgM Antibody ELISA is an immunoassay, which employs synthetic and recombinant HEV antigens for the detection of IgM antibody to HEV in human serum or plasma. These antigens, which correspond to the structure regions of HEV, constitute the solid phase antigenic adsorbent. Samples with O.D. values greater than or equal to the Cut-off value are defined as initially reactive. Initially reactive specimens are to be re-tested in duplicate. Samples, which do not react in either of the duplicate, repeat tests are considered non-reactive for IgM antibodies to HEV. Samples, which are reactive in either of the duplicates tests, are considered repeatably reactive. Rev. (3/4) HEV IgM

Pathways: TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy