TGFBR2 ELISA Kit

Catalog No. ABIN6719763

Product Details TGFBR2 ELISA Kit

Target: TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))

Reactivity: Human

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Detection Range: 15.6 pg/mL - 1000 pg/mL

Minimum Detection Limit: 15.6 pg/mL

Application: ELISA

Purpose: Sandwich ELISA for Quantitative Detection of Antigen

Sample Type: Cell Culture Supernatant, Plasma (EDTA - heparin), Serum

Analytical Method: Quantitative

Characteristics:

Synonyms: AAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TbetaR-II, TGF-beta receptor type II, TGF-beta receptor type-2, TGF-beta type II receptor, TGFbeta RII, Tgfbr2, TGFR 2, TGFR-2, TGFR2_HUMAN, Transforming growth factor beta receptor II (70/80 kDa), Transforming growth factor-beta receptor type II

Background: TGFBR2(transforming growth factor, beta receptor II (70/80 kDa)), also known as TGF-beta receptor type-2, TGFR-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II( TGF-beta receptor type II, TbetaR-II), is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. A TGFBR2 cDNA encoding a deduced 565-amino acid protein with a calculated molecular mass of approximately 60 kD in length. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different informs have been cha...

Gene Name: TGFBR2

Production: Natural and recombinant human TGFBR2. There is no detectable cross-reactivity with other relevant proteins.

Standard: Expression system for standard: NSO, Immunogen sequence: I24-D159

Application Details

Application Notes:

Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.2pg/mL, 15.6pg/mL human TGFBR2 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. It is recommended that each human TGFBR2 standard solution and each sample be measured in duplicate.

Blood Product Anticoagulant: Heparin Sodium

ELISA Dilution: 15.6pg/mL-1000pg/mL

Sample Volume: 100 μL

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: RT,4 °C,-20 °C

Storage Comment: Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.

Target Details for TGFBR2

Target: TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))

Alternative Name: TGFBR2 (TGFBR2 Products)

Synonyms: AAT3 ELISA Kit, FAA3 ELISA Kit, LDS1B ELISA Kit, LDS2B ELISA Kit, MFS2 ELISA Kit, RIIC ELISA Kit, TAAD2 ELISA Kit, TGFR-2 ELISA Kit, TGFbeta-RII ELISA Kit, 1110020H15Rik ELISA Kit, AU042018 ELISA Kit, DNIIR ELISA Kit, RIIDN ELISA Kit, TBR-II ELISA Kit, TbetaR-II ELISA Kit, TbetaRII ELISA Kit, TGFBR2 ELISA Kit, TBETA-RII ELISA Kit, TGFBRII ELISA Kit, TGF-beta 2 ELISA Kit, Tgfbr2T ELISA Kit, cb537 ELISA Kit, tgfbr2 ELISA Kit, wu:fj05c10 ELISA Kit, zgc:110498 ELISA Kit, transforming growth factor beta receptor 2 ELISA Kit, transforming growth factor, beta receptor II ELISA Kit, transforming growth factor, beta receptor 2 ELISA Kit, transforming growth factor beta receptor 2b ELISA Kit, TGFBR2 ELISA Kit, Tgfbr2 ELISA Kit, tgfbr2b ELISA Kit

Gene ID: 7048

NCBI Accession: NP_001020018

UniProt: P37173