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Kv1.6/KCNA6 Products

(Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 6 (KCNA6))

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Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class. The coding region of this gene is intronless, and the gene is clustered with genes KCNA1 and KCNA5 on chromosome 12. [provided by RefSeq, Jul 2008].

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Featured Kv1.6/KCNA6 Categories

Kv1.6/KCNA6 Antibodies

High quality antibodies with extensive validation data.

Kv1.6/KCNA6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Kv1.6/KCNA6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7163953
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN1538816
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7163956
Quantity 100 μg
Datasheet Datasheet

Recommended Kv1.6/KCNA6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3113020
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3135479
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Kv1.6/KCNA6 products

Dufour, Woodhouse, Goaillard: "Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development." in: Journal of neuroscience research, Vol. 92, Issue 8, pp. 981-99, (2014) (PubMed).

Ovsepian, Steuber, Le Berre, OHara, OLeary, Dolly: "A defined heteromeric KV1 channel stabilizes the intrinsic pacemaking and regulates the output of deep cerebellar nuclear neurons to thalamic targets." in: The Journal of physiology, Vol. 591, Issue Pt 7, pp. 1771-91, (2013) (PubMed).

He, Shao, Rittase, Bausch: "Increased Kv1 channel expression may contribute to decreased sIPSC frequency following chronic inhibition of NR2B-containing NMDAR." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 37, Issue 6, pp. 1338-56, (2012) (PubMed).

Irani, Pettingill, Kleopa, Schiza, Waters, Mazia, Zuliani, Watanabe, Lang, Buckley, Vincent: "Morvan syndrome: clinical and serological observations in 29 cases." in: Annals of neurology, Vol. 72, Issue 2, pp. 241-55, (2012) (PubMed).

Fulton, Thibault, Mendez, Lahaie, Tirotta, Borrelli, Bouvier, Tempel, Trudeau: "Contribution of Kv1.2 voltage-gated potassium channel to D2 autoreceptor regulation of axonal dopamine overflow." in: The Journal of biological chemistry, Vol. 286, Issue 11, pp. 9360-72, (2011) (PubMed).

Prüss, Dewes, Derst, Fernández-Klett, Veh, Priller: "Potassium channel expression in adult murine neural progenitor cells." in: Neuroscience, Vol. 180, pp. 19-29, (2011) (PubMed).

Al-Sabi, Kaza, Le Berre, OHara, Bodeker, Wang, Dolly: "Position-dependent attenuation by Kv1.6 of N-type inactivation of Kv1.4-containing channels." in: The Biochemical journal, Vol. 438, Issue 2, pp. 389-96, (2011) (PubMed).

Gazula, Strumbos, Mei, Chen, Rahner, Kaczmarek: "Localization of Kv1.3 channels in presynaptic terminals of brainstem auditory neurons." in: The Journal of comparative neurology, Vol. 518, Issue 16, pp. 3205-20, (2010) (PubMed).

Synonyms and alternative names related to Kv1.6/KCNA6

potassium voltage-gated channel subfamily A member 6 (KCNA6), potassium voltage-gated channel subfamily A member 6 (Kcna6), potassium voltage-gated channel, shaker-related, subfamily, member 6 (Kcna6), HBK2, Kv1.6, KV1.6, MK1.6

Protein level used designations for Kv1.6/KCNA6

  • potassium voltage-gated channel subfamily A member 6
  • RCK2
  • kv2
  • potassium channel-Kv2
  • voltage-gated potassium channel subunit Kv1.6
  • voltage-gated potassium channel subunit Kv2
  • human brain potassium channel-2
  • voltage-gated potassium channel HBK2
  • voltage-gated potassium channel protein Kv1.6
  • potassium voltage gated channel, shaker related, subfamily, member 6
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