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LTA Products

(Lymphotoxin-alpha (LTA))

Categories

The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012].

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Featured LTA Categories

LTA Antibodies

High quality antibodies with extensive validation data.

LTA ELISA Kits

Reliable ELISA kits for a wide range of species.

LTA Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LTA Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7431161
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7425722
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN652448
Quantity 400 μL
Datasheet Datasheet

Recommended LTA ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6957573
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6957572
Quantity 96 tests
Datasheet Datasheet
Reactivity Dog
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968386
Quantity 96 tests
Datasheet Datasheet

Recommended LTA Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Chemical
Source Escherichia coli (E. coli)
Validations
  • (2)
Cat. No. ABIN5509392
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293T Cells
Validations
  • (2)
Cat. No. ABIN1309863
Quantity 25 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123805
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our LTA products

Liu, Yu, Wang, Dong: "MicroRNA-345-5p regulates depression by targeting suppressor of cytokine signaling 1." in: Brain and behavior, Vol. 10, Issue 9, pp. e01653, (2020) (PubMed).

Li, Zhang, Wang, Zhao, Zhang, Ding, Wei: "Aging affects responsiveness of peripheral blood mononuclear cells to immunosuppression of periodontal ligament stem cells." in: The Journal of international medical research, Vol. 48, Issue 7, pp. 300060520930853, (2020) (PubMed).

Laskowska, Jarosz, Grądzki et al.: "Effect of Multi-Microbial Probiotic Formulation Bokashi on Pro- and Anti-Inflammatory Cytokines Profile in the Serum, Colostrum and Milk of Sows, and in a Culture of Polymorphonuclear Cells Isolated ..." in: Probiotics and antimicrobial proteins, Vol. 11, Issue 1, pp. 220-232, (2019) (PubMed).

Faure, Bruzzese, Steinberg, Jammes, Torrents, Berdah, Garnier, Legris, Loundou, Chalopin, Magalon, Guieu, Fenouillet, Lechevallier: "Effectiveness of pure argon for renal transplant preservation in a preclinical pig model of heterotopic autotransplantation." in: Journal of translational medicine, Vol. 14, pp. 40, (2016) (PubMed).

Wang, Zheng, Meng, Wang, He, Zhang, Liu, Hu, He, Hu, Wang: "In vivo study of immunogenicity and kinetic characteristics of a quantum dot-labelled baculovirus." in: Biomaterials, Vol. 64, pp. 78-87, (2015) (PubMed).

Johnson, Drugan, Miller, Evans: "38" in: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991)

Akelma, Cizmeci, Kanburoglu, Bozkaya, Catal, Mete, Kutukoglu, Namuslu: "Elevated level of serum osteopontin in school-age children with asthma." in: Allergologia et immunopathologia, Vol. 42, Issue 4, pp. 275-81, (2014) (PubMed).

Kallio, Marchesani, Vlachopoulou, Mäntylä, Paju, Buhlin, Suominen, Contreras, Knuuttila, Hernandez, Huumonen, Nieminen, Perola, Sinisalo, Lokki, Pussinen: "Genetic variation on the BAT1-NFKBIL1-LTA region of major histocompatibility complex class III associates with periodontitis." in: Infection and immunity, Vol. 82, Issue 5, pp. 1939-48, (2014) (PubMed).

Jeong, Kim, Moon, Song, Choi, Kim, Kim, An: "Targeted inhibition of phosphatidyl inositol-3-kinase p110?, but not p110?, enhances apoptosis and sensitivity to paclitaxel in chemoresistant ovarian cancers." in: Apoptosis : an international journal on programmed cell death, Vol. 18, Issue 4, pp. 509-20, (2013) (PubMed).

Yu, Zhu, Gu, Li, Wang, Liu, Wei, Li: "Simvastatin attenuates sympathetic hyperinnervation to prevent atrial fibrillation during the postmyocardial infarction remodeling process." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 113, Issue 12, pp. 1937-44, (2012) (PubMed).

Synonyms and alternative names related to LTA

lymphotoxin alpha (LTA), lymphotoxin A (Lta), lymphotoxin alpha (Lta), hlb382, LT, LT-alpha, LT-[a], LTalpha, Ltx, LT[a], TNF-beta, TNFB, Tnfb, TNFSF1, Tnfsf1b

Protein level used designations for LTA

  • LT-alpha
  • TNF superfamily, member 1
  • TNF-beta
  • lymphotoxin-alpha
  • tumor necrosis factor beta
  • tumor necrosis factor ligand superfamily member 1
  • TNF beta
  • lymphotoxin alpha
  • lymphotoxin A
  • lymphotoxin alpha (TNF superfamily, member 1)
  • Lymphotoxin-alpha
  • tumour necrosis factor beta
  • ATP-binding cassette, sub-family F (GCN20), member 1
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