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LTC4S Products

(Leukotriene C4 Synthase (LTC4S))
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum. [provided by RefSeq, Jul 2008].

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Featured LTC4S Categories

LTC4S Antibodies

High quality antibodies with extensive validation data.

LTC4S ELISA Kits

Reliable ELISA kits for a wide range of species.

LTC4S Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LTC4S Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IF, IHC
Validations
  • (2)
Cat. No. ABIN7158304
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Pig
Application WB
Validations
  • (4)
  • (1)
Cat. No. ABIN6746296
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN652524
Quantity 400 μL
Datasheet Datasheet

Recommended LTC4S ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968290
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1140617
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1140619
Quantity 96 tests
Datasheet Datasheet

Recommended LTC4S Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309878
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3100266
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3122768
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our LTC4S products

Tang, Sally, Lesko, Discepolo, Abadie, Ciszewski, Semrad, Guandalini, Kupfer, Jabri: "Cysteinyl leukotrienes mediate lymphokine killer activity induced by NKG2D and IL-15 in cytotoxic T cells during celiac disease." in: The Journal of experimental medicine, Vol. 212, Issue 10, pp. 1487-95, (2015) (PubMed).

Niegowski, Kleinschmidt, Ahmad, Qureshi, Mårback, Rinaldo-Matthis, Haeggström: "Structure and inhibition of mouse leukotriene C4 synthase." in: PLoS ONE, Vol. 9, Issue 5, pp. e96763, (2014) (PubMed).

Nishibe, Parry, Ishida, Aziz, Murray, Patel, Rahman, Strand, Saito, Saito, Hammond, Savidge, Mackman, Wijelath: "Oncostatin M promotes biphasic tissue factor expression in smooth muscle cells: evidence for Erk-1/2 activation." in: Blood, Vol. 97, Issue 3, pp. 692-9, (2001) (PubMed).

Pimentel-Muiños, Seed: "Regulated commitment of TNF receptor signaling: a molecular switch for death or activation." in: Immunity, Vol. 11, Issue 6, pp. 783-93, (2000) (PubMed).

Kieran, Blank, Logeat, Vandekerckhove, Lottspeich, Le Bail, Urban, Kourilsky, Baeuerle, Israël: "The DNA binding subunit of NF-kappa B is identical to factor KBF1 and homologous to the rel oncogene product." in: Cell, Vol. 62, Issue 5, pp. 1007-18, (1990) (PubMed).

Baeuerle, Baltimore: "Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor." in: Cell, Vol. 53, Issue 2, pp. 211-7, (1988) (PubMed).

Synonyms and alternative names related to LTC4S

leukotriene C4 synthase (Ltc4s), leukotriene C4 synthase (LTC4S), leukotriene C4 synthase-like (LTC4SL), leukotriene C4 synthase, gene 1 (ltc4s.1), leukotriene C4 synthase (ltc4s), LTC4S, ltc4s, si:dkey-33h4.2

Protein level used designations for LTC4S

  • LTC4 synthase
  • leukotriene-C(4) synthase
  • leukotriene C4 synthase
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