CD86 (human): 293T Lysate
CD86
WB
Whole Cell Lysate
Overexpression Lysate
HEK 293T Cells
1 image
(6 references)-
- Target See all CD86 products
- CD86
- Species of Lysate
- Human Cells
- Application
- Western Blotting (WB)
- Characteristics
- Cluster of Differentiation 86 (also known as CD86 and B7-2) is a protein expressed on antigen- presenting cells that provides costimulatory signals necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD86 works in tandem with CD80 to prime T cells. The CD86 gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. CD86+ macrophages in Hodgkin lymphoma patients are an independent marker for potential nonresponse to firstline-therapy. Lysate of human CD86 transfected 293T cells
- Lysed Cells
- HEK 293T Cells
- Lysate Type
- Overexpression Lysate
- Lysate Fraction
- Whole Cell Lysate
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CD86 293T Cell Transient Overexpression Lysate(Denatured)
CD86 WB Whole Cell Lysate Overexpression Lysate HEK 293T Cells Reactivity: Human
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- Application Notes
- CD86 (h): 293T Lysate is suitable as a Western Blotting positive control for human reactive CD86 antibodies. Recommended use: 10-20 µl per lane. Control 293T Lysate: H86LYS is available as a Western Blotting negative control lysate derived from non-transfected 293T cells.
- Restrictions
- For Research Use only
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- Handling Advice
- Repeated freezing and thawing should be minimized. Sample vial should be boiled once prior to use. Non-hazardous. No MSDS required.
- Storage
- -20 °C
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: "Closer association of IA-2 humoral autoreactivity with HLA DR3/4 than DQB1*0201/*0302 in Korean T1D patients." in: Annals of the New York Academy of Sciences, Vol. 1037, pp. 104-9, (2005) (PubMed).
: "Association of HLA-DR, -DQ genotype and CTLA-4 gene polymorphism with Graves' disease in Japanese children." in: Hormone research, Vol. 63, Issue 2, pp. 55-60, (2005) (PubMed).
: "Anti-HLA class II antibodies in kidney retransplant patients." in: Tissue antigens, Vol. 65, Issue 4, pp. 370-8, (2005) (PubMed).
: "Distinct tumour necrosis factor alpha, interferon gamma, interleukin 10, and cytotoxic T cell antigen 4 gene polymorphisms in disease occurrence and end stage renal disease in Wegener's granulomatosis." in: Annals of the rheumatic diseases, Vol. 64, Issue 3, pp. 457-61, (2005) (PubMed).
: "Association of Helicobacter pylori-related distal gastric cancer with the HLA class II gene DQB10602 and cagA strains in a southern European population." in: Helicobacter, Vol. 10, Issue 1, pp. 12-21, (2005) (PubMed).
: "Allelic polymorphism in introns 1 and 2 of the HLA-DQA1 gene." in: Tissue antigens, Vol. 65, Issue 1, pp. 56-66, (2005) (PubMed).
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: "Closer association of IA-2 humoral autoreactivity with HLA DR3/4 than DQB1*0201/*0302 in Korean T1D patients." in: Annals of the New York Academy of Sciences, Vol. 1037, pp. 104-9, (2005) (PubMed).
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- Target
- CD86
- Alternative Name
- CD86 (CD86 Products)
- Synonyms
- B7-2 Lysate, B7.2 Lysate, B70 Lysate, CD28LG2 Lysate, LAB72 Lysate, B7 Lysate, CLS1 Lysate, Cd28l2 Lysate, ETC-1 Lysate, Ly-58 Lysate, Ly58 Lysate, MB7 Lysate, MB7-2 Lysate, TS/A-2 Lysate, CD86 molecule Lysate, CD86 antigen Lysate, integrin subunit alpha 2b Lysate, CD86 Lysate, Cd86 Lysate, Itga2b Lysate
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