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MAP4K1 Products

(Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))
May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation.

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Featured MAP4K1 Categories

MAP4K1 Antibodies

High quality antibodies with extensive validation data.

MAP4K1 ELISA Kits

Reliable ELISA kits for a wide range of species.

MAP4K1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MAP4K1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
  • (4)
Cat. No. ABIN710396
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, ICC, IF
Validations
  • (3)
Cat. No. ABIN6258396
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN1327132
Quantity 100 μg
Datasheet Datasheet

Recommended MAP4K1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968656
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1142984
Quantity 96 tests
Datasheet Datasheet

Recommended MAP4K1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310246
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310245
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3093652
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MAP4K1 products

Wissing, Jänsch, Nimtz, Dieterich, Hornberger, Kéri, Wehland, Daub: "Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 3, pp. 537-47, (2007) (PubMed).

Brenner, Golks, Kiefer, Krammer, Arnold: "Activation or suppression of NFkappaB by HPK1 determines sensitivity to activation-induced cell death." in: The EMBO journal, Vol. 24, Issue 24, pp. 4279-90, (2005) (PubMed).

Boomer, Tan: "Functional interactions of HPK1 with adaptor proteins." in: Journal of cellular biochemistry, Vol. 95, Issue 1, pp. 34-44, (2005) (PubMed).

Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, (2004) (PubMed).

Sawasdikosol, Russo, Burakoff: "Hematopoietic progenitor kinase 1 (HPK1) negatively regulates prostaglandin E2-induced fos gene transcription." in: Blood, Vol. 101, Issue 9, pp. 3687-9, (2003) (PubMed).

Schulze-Luehrmann, Santner-Nanan, Jha, Schimpl, Avots, Serfling: "Hematopoietic progenitor kinase 1 supports apoptosis of T lymphocytes." in: Blood, Vol. 100, Issue 3, pp. 954-60, (2002) (PubMed).

Hu, Qiu, Wang, Meyer, Tan: "Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade." in: Genes & development, Vol. 10, Issue 18, pp. 2251-64, (1996) (PubMed).

Synonyms and alternative names related to MAP4K1

mitogen activated protein kinase kinase kinase kinase 1 (Map4k1), mitogen-activated protein kinase kinase kinase kinase 1 (MAP4K1), mitogen-activated protein kinase kinase kinase kinase 1 (Map4k1), HPK1, Hpk1, mHPK1

Protein level used designations for MAP4K1

  • mitogen-activated protein kinase kinase kinase kinase 1
  • MAPK/ERK kinase kinase kinase 1
  • MEK kinase kinase 1
  • MEKKK 1
  • hematopoietic progenitor kinase 1
  • HPK
  • mitogen activated protein kinase kinase kinase kinase 1
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