MAX Products
(MYC Associated Factor X (MAX))
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The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].
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Featured MAX Categories
MAX Antibodies
High quality antibodies with extensive validation data.
MAX ELISA Kits
Reliable ELISA kits for a wide range of species.
MAX Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MAX Antibodies
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ABIN184586
Quantity
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Datasheet
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ABIN561745
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Recommended MAX ELISA Kits
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ABIN6968708
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Cat. No.
ABIN3083329
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Reactivity
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Latest Publications for our MAX products
: "lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer." in: Cancer cell, Vol. 33, Issue 4, pp. 706-720.e9, (2019) (PubMed).: "Pattern recognition receptor mediated downregulation of microRNA-650 fine-tunes MxA expression in dendritic cells infected with influenza A virus." in: European journal of immunology, Vol. 46, Issue 1, pp. 167-77, (2016) (PubMed).
: "Transcription factors with conserved binding sites near ATOH1 on the POU4F3 gene enhance the induction of cochlear hair cells." in: Molecular neurobiology, Vol. 51, Issue 2, pp. 672-84, (2015) (PubMed).
: "Opposing effects of HIF1α and HIF2α on chromaffin cell phenotypic features and tumor cell proliferation: Insights from MYC-associated factor X." in: International journal of cancer, Vol. 135, Issue 9, pp. 2054-64, (2014) (PubMed).
: "Max is acetylated by p300 at several nuclear localization residues." in: The Biochemical journal, Vol. 403, Issue 3, pp. 397-407, (2007) (PubMed).
: "HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity." in: Cancer cell, Vol. 11, Issue 4, pp. 335-47, (2007) (PubMed).
: "SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes." in: Molecular cell, Vol. 24, Issue 5, pp. 771-83, (2006) (PubMed).
: "Expression of matrix metalloproteinase-9 in endothelial cells is differentially regulated by shear stress. Role of c-Myc." in: The Journal of biological chemistry, Vol. 278, Issue 35, pp. 32994-9, (2003) (PubMed).
: "Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc." in: Science (New York, N.Y.), Vol. 251, Issue 4998, pp. 1211-7, (1991) (PubMed).
Synonyms and alternative names related to MAX
CG9648 gene product from transcript CG9648-RD (Max), MYC associated factor X L homeolog (max.L), MYC associated factor X (MAX), MYC associated factor X (max), Max protein (Max), MYC associated factor X S homeolog (max.S), MYC associated factor X (Max), myc associated factor X (max), AA960152, AI875693, bhlhd4, bHLHd4, bhlhd5, bHLHd5, bhlhd6, bHLHd6, bhlhd7, bHLHd7, bhlhd8, bHLHd8, bHLHd9, CG9648, dMax, dmax, Dmel\\CG9648, fa92b04, fb52a04, fb95h11, MAX, max, wu:fa92b04, wu:fb52a04, wu:fb95h11, xmax, xmax2, xmax4, zmaxProtein level used designations for MAX
- CG9648-PA
- CG9648-PC
- Max-PA
- Max-PC
- Max homologue 2
- Myc binding protein Xmax4
- myc-associated factor X
- protein max
- xMAX
- MYC associated factor X
- myc-binding novel HLH/LZ protein
- protein myn
- class D basic helix-loop-helix protein 4
- Myc binding protein Xmax2
Did you look for something else?
- MAVS
- MAUB
- MAUA
- MAU2/KIAA0892
- Matrix-Remodelling Associated 8
- Matrix Metallopeptidase 23
- Matrix Metallopeptidase 14 (Membrane-inserted)
- Matrix Metallopeptidase 1 (Interstitial Collagenase)
- Matrilin 3
- MATR3
- MATN4
- MATN2
- MATN1
- MATK
- Maternal Effect Embryo Arrest 12 Protein
- MATALPHA2
- MAT2B
- MAT2A
- MAT1A
- MAT1/2A
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