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MBNL1 Products

(Muscleblind-like Protein 1 (MBNL1))
Involved in pre-mRNA alternative splicing regulation. Binds to CUG triplet repeat in RNA (By similarity).

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Featured MBNL1 Categories

MBNL1 Antibodies

High quality antibodies with extensive validation data.

MBNL1 ELISA Kits

Reliable ELISA kits for a wide range of species.

MBNL1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MBNL1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (1)
  • (5)
Cat. No. ABIN561753
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF, IHC (p)
Validations
  • (3)
Cat. No. ABIN574297
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7264101
Quantity 200 μL
Datasheet Datasheet

Recommended MBNL1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1143401
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1143402
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1143400
Quantity 96 tests
Datasheet Datasheet

Recommended MBNL1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (2)
Cat. No. ABIN2725584
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310480
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310482
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our MBNL1 products

Coram, Stillwagon, Guggilam, Jenkins, Swanson, Ladd: "Muscleblind-like 1 is required for normal heart valve development in vivo." in: BMC developmental biology, Vol. 15, pp. 36, (2015) (PubMed).

Rehman, Gladman, Periasamy, Sun, Mahadevan: "Development of an AP-FRET based analysis for characterizing RNA-protein interactions in myotonic dystrophy (DM1)." in: PLoS ONE, Vol. 9, Issue 4, pp. e95957, (2014) (PubMed).

Echeverria, Cooper: "Muscleblind-like 1 activates insulin receptor exon 11 inclusion by enhancing U2AF65 binding and splicing of the upstream intron." in: Nucleic acids research, Vol. 42, Issue 3, pp. 1893-903, (2014) (PubMed).

Sen, Talukdar, Liu, Tam, Reddy, Webster: "Muscleblind-like 1 (Mbnl1) promotes insulin receptor exon 11 inclusion via binding to a downstream evolutionarily conserved intronic enhancer." in: The Journal of biological chemistry, Vol. 285, Issue 33, pp. 25426-37, (2010) (PubMed).

Arambula, Ramisetty, Baranger, Zimmerman: "A simple ligand that selectively targets CUG trinucleotide repeats and inhibits MBNL protein binding." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 38, pp. 16068-73, (2009) (PubMed).

Cardani, Baldassa, Botta, Rinaldi, Novelli, Mancinelli, Meola: "Ribonuclear inclusions and MBNL1 nuclear sequestration do not affect myoblast differentiation but alter gene splicing in myotonic dystrophy type 2." in: Neuromuscular disorders : NMD, Vol. 19, Issue 5, pp. 335-43, (2009) (PubMed).

Holt, Jacquemin, Fardaei, Sewry, Butler-Browne, Furling, Brook, Morris: "Muscleblind-like proteins: similarities and differences in normal and myotonic dystrophy muscle." in: The American journal of pathology, Vol. 174, Issue 1, pp. 216-27, (2009) (PubMed).

Teplova, Patel: "Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1." in: Nature structural & molecular biology, Vol. 15, Issue 12, pp. 1343-51, (2008) (PubMed).

Warf, Berglund: "MBNL binds similar RNA structures in the CUG repeats of myotonic dystrophy and its pre-mRNA substrate cardiac troponin T." in: RNA (New York, N.Y.), Vol. 13, Issue 12, pp. 2238-51, (2007) (PubMed).

Adam-Vizi: "Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and non-electron transport chain sources." in: Antioxidants & redox signaling, Vol. 7, Issue 9-10, pp. 1140-9, (2005) (PubMed).

Synonyms and alternative names related to MBNL1

muscleblind like splicing regulator 1 (MBNL1), muscleblind like splicing regulator 1 (mbnl1), muscleblind-like splicing regulator 1 (mbnl1), muscleblind like splicing factor 1 (Mbnl1), muscleblind-like splicing regulator 1 (Mbnl1), EXP, EXP35, EXP40, EXP42, Mbnl, MBNL, MBNL1, mKIAA0428, zgc:153954

Protein level used designations for MBNL1

  • muscleblind-like
  • muscleblind-like (Drosophila)
  • muscleblind-like protein 1
  • muscleblind-like 1
  • triplet-expansion RNA-binding protein
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