MCAM Proteins
(Melanoma Cell Adhesion Molecule (MCAM))
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
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22 results :
MCAM
Origin: Human
Host: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
MCAM
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
MCAM
Origin: Human
Host: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
1 reference
MCAM
Origin: Human
Host: HEK-293T Cells
Recombinant
SDS, WB, ELISA, PI
2 images
MCAM
Origin: Human
Host: Baculovirus infected Insect Cells
Recombinant
> 95% by SDS-PAGE
SDS
1 image
MCAM
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
MCAM
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
MCAM
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
MCAM
Origin: Human
Host: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
MCAM
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
SDS, WB, ELISA
MCAM
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
SDS, WB, ELISA
MCAM
Origin: Human
Host: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
SDS, WB, Imm, ELISA, AcA
Active
MCAM
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
MCAM
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
MCAM
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS, WB, Imm, PC
MCAM
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS
1 image
MCAM
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, ELISA, IP
1 image
MCAM
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Latest Publications for our MCAM Proteins
: "The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis." in: Nature communications, Vol. 8, pp. 15279, (2018) (PubMed).: "Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis." in: Cell research, Vol. 27, Issue 3, pp. 352-372, (2017) (PubMed).
: "CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development." in: Cell research, Vol. 25, Issue 3, pp. 275-87, (2015) (PubMed).
: "Selection of scFv Antibody Fragments Binding to Human Blood versus Lymphatic Endothelial Surface Antigens by Direct Cell Phage Display." in: PLoS ONE, Vol. 10, Issue 5, pp. e0127169, (2015) (PubMed).
: "Monoclonal antibodies to human laminin ?4 chain globular domain inhibit tumor cell adhesion and migration on laminins 411 and 421, and binding of ?6?1 integrin and MCAM to ?4-laminins." in: Matrix biology : journal of the International Society for Matrix Biology, Vol. 36, pp. 5-14, (2014) (PubMed).
: "Wnt5a uses CD146 as a receptor to regulate cell motility and convergent extension." in: Nature communications, Vol. 4, pp. 2803, (2013) (PubMed).
: "Up-regulation of MUC18 in airway epithelial cells by IL-13: implications in bacterial adherence." in: American journal of respiratory cell and molecular biology, Vol. 44, Issue 5, pp. 606-13, (2011) (PubMed).
Aliases for MCAM Proteins
melanoma cell adhesion molecule (MCAM) Proteinsmelanoma cell adhesion molecule (Mcam) Proteins
melanoma cell adhesion molecule b (mcamb) Proteins
1-gicerin Proteins
AV025631 Proteins
CD146 Proteins
cd146 Proteins
CD149 Proteins
gicerin Proteins
id:ibd3512 Proteins
mcam Proteins
MCAM Proteins
MUC18 Proteins
Muc18 Proteins
s-endo Proteins
s-gicerin Proteins
Did you look for something else?
- MC4R Proteins
- MC3R Proteins
- MC1 Receptor Proteins
- MBTPS2 Proteins
- MBTPS1 Proteins
- MBTD1 Proteins
- MBP/MBL Proteins
- MBP Proteins
- MBOAT7 Proteins
- MBOAT4 Proteins
- MBOAT2 Proteins
- MBOAT1 Proteins
- MBNL3 Proteins
- MBNL2 Proteins
- MBNL1 Proteins
- MBL2 Proteins
- MBIP Proteins
- MBD5 Proteins
- MBD4 Proteins
- MBD3L2 Proteins
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