MCOLN1 Products
(Mucolipin 1 (MCOLN1))
Categories
This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+), Fe(2+), Na(+), K(+), and H(+), and is modulated by changes in Ca(2+) concentration. Mutations in this gene result in mucolipidosis type IV. [provided by RefSeq, Oct 2009].
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Featured MCOLN1 Categories
MCOLN1 Antibodies
High quality antibodies with extensive validation data.
MCOLN1 ELISA Kits
Reliable ELISA kits for a wide range of species.
MCOLN1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MCOLN1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (4)
Cat. No.
ABIN2776233
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN657474
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Bat, Dog, Human, Monkey, Pig, Rabbit
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN214172
Quantity
50 μg
Datasheet
Datasheet
Recommended MCOLN1 ELISA Kits
Recommended MCOLN1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310569
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3117981
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3127838
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our MCOLN1 products
: "A NOVEL NOX/PHOX-CD38-NAADP-TFEB AXIS IMPORTANT FOR MACROPHAGE ACTIVATION DURING BACTERIAL PHAGOCYTOSIS." in: Autophagy, Vol. 18, Issue 1, pp. 124-141, (2022) (PubMed).: "Vitamin D3 activates the autolysosomal degradation function against Helicobacter pylori through the PDIA3 receptor in gastric epithelial cells." in: Autophagy, Vol. 15, Issue 4, pp. 707-725, (2019) (PubMed).
: "Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis." in: Autophagy, pp. 1-20, (2019) (PubMed).
: "Differential regulation of TRP channel gene and protein expression by intervertebral disc degeneration and back pain." in: Scientific reports, Vol. 9, Issue 1, pp. 18889, (2019) (PubMed).
: "Defective autophagosome trafficking contributes to impaired autophagic flux in coronary arterial myocytes lacking CD38 gene." in: Cardiovascular research, Vol. 102, Issue 1, pp. 68-78, (2014) (PubMed).
: "Lysosomal localization of TRPML3 depends on TRPML2 and the mucolipidosis-associated protein TRPML1." in: The Journal of biological chemistry, Vol. 281, Issue 25, pp. 17517-27, (2006) (PubMed).
Synonyms and alternative names related to MCOLN1
mucolipin 1a (mcoln1a), mucolipin 1 (MCOLN1), mucolipin 1 L homeolog (mcoln1.L), mucolipin 1 (mcoln1), mucolipin 1 (LOAG_04987), mucolipin 1 (Mcoln1), 2210015I05Rik, mcoln1, MCOLN1, mcoln1.1, MG-2, ML4, MLIV, mln1, MST080, mucolipidin, mucolipin-1, TRP-ML1, TRPM-L1, TRPML1, zgc:63619Protein level used designations for MCOLN1
- mucolipin 1
- mucolipin 1.1
- mucolipidin
- mucolipidosis type IV protein
- mucolipin-1
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