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ME1 Products

(Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))

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This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. [provided by RefSeq, Jul 2008].

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Featured ME1 Categories

ME1 Antibodies

High quality antibodies with extensive validation data.

ME1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ME1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC, IP
Validations
  • (6)
Cat. No. ABIN2855777
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (1)
  • (5)
Cat. No. ABIN561774
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7160996
Quantity 100 μg
Datasheet Datasheet

Recommended ME1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6231269
Quantity 96 tests
Datasheet Datasheet

Recommended ME1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123839
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310614
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3083384
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ME1 products

Uddin, Mahmood, Ibrahim, Briski: "Sex-Dimorphic Estrogen Receptor Regulation of Ventromedial Hypothalamic Nucleus Glucoregulatory Neuron Adrenergic Receptor Expression in Hypoglycemic Male and Female Rats." in: Brain research, pp. 146311, (2019) (PubMed).

Gdynia, Sauer, Kopitz, Fuchs, Duglova, Ruppert, Miller, Pahl, Cerwenka, Enders, Mairbäurl, Kamiński, Penzel, Zhang, Fuller, Wade, Benner, Chang-Claude, Brenner, Hoffmeister, Zentgraf, Schirmacher et al.: "The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration. ..." in: Nature communications, Vol. 7, pp. 10764, (2016) (PubMed).

Al-Dwairi, Brown, Pabona, Van, Hamdan, Mercado, Quick, Wight, Simmen, Simmen: "Enhanced Gastrointestinal Expression of Cytosolic Malic Enzyme (ME1) Induces Intestinal and Liver Lipogenic Gene Expression and Intestinal Cell Proliferation in Mice." in: PLoS ONE, Vol. 9, Issue 11, pp. e113058, (2014) (PubMed).

Kato, Nicholson, Neiman, Rantalainen, Holmes, Barrett, Uhlén, Nilsson, Spector, Schwenk: "Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model." in: Proteome science, Vol. 9, pp. 73, (2011) (PubMed).

Heart, Cline, Collis, Pongratz, Gray, Smith: "Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion." in: American journal of physiology. Endocrinology and metabolism, Vol. 296, Issue 6, pp. E1354-62, (2009) (PubMed).

Synonyms and alternative names related to ME1

malic enzyme 1 (ME1), malic enzyme 1, NADP(+)-dependent, cytosolic (Me1), malic enzyme 1 (Me1), malic enzyme 1, NADP(+)-dependent, cytosolic (me1), malic enzyme 1, NADP(+)-dependent, cytosolic (ME1), D9Ertd267e, HUMNDME, Mdh-1, ME1, MES, Mod-1, Mod1, MOD1, zgc:153079

Protein level used designations for ME1

  • Malic enzyme, cytoplasmic
  • NADP-ME
  • NADP-dependent malic enzyme
  • malate dehydrogenase
  • malic enzyme 1, soluble
  • pyruvic-malic carboxylase
  • malic enzyme, supernatant
  • cytosolic malic enzyme 1
  • malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
  • malate dehydrogenase decarboxylase (NADP+)
  • malic enzyme 1, NADP(+)-dependent, cytoplasmic (cytosolic, soluble)
  • malic enzyme 1, NADP(+)-dependent, cytosolic
  • cytosolic malic enzyme 1-like
  • NADP-dependent malic enzyme-like
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