NBR1 Products
(Neighbor of BRCA1 Gene 1 (NBR1))
Categories
The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled coil motif, which is present in many genes with transformation potential, but the function of this protein is unknown. This gene is located on a region of chromosome 17q21.1 that is in close proximity to tumor suppressor gene BRCA1. Three alternatively spliced variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].
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Featured NBR1 Categories
NBR1 Antibodies
High quality antibodies with extensive validation data.
NBR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
NBR1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NBR1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (5)
Cat. No.
ABIN1680974
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (4)
Cat. No.
ABIN561705
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (7)
- (2)
Cat. No.
ABIN517601
Quantity
100 μg
Datasheet
Datasheet
Recommended NBR1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968819
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6208870
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1145033
Quantity
96 tests
Datasheet
Datasheet
Recommended NBR1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312051
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1780821
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3094033
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our NBR1 products
: "Autophagy induction in atrophic muscle cells requires ULK1 activation by TRIM32 through unanchored K63-linked polyubiquitin chains. ..." in: Science advances, Vol. 5, Issue 5, pp. eaau8857, (2019) (PubMed).: "Depletion of NBR1 in urothelial carcinoma cells enhances rapamycin-induced apoptosis through impaired autophagy and mitochondrial dysfunction." in: Journal of cellular biochemistry, (2019) (PubMed).
: "Clinical isolates of the modern Mycobacterium tuberculosis lineage 4 evade host defense in human macrophages through eluding IL-1β-induced autophagy." in: Cell death & disease, Vol. 9, Issue 6, pp. 624, (2018) (PubMed).
: "NBR1 enables autophagy-dependent focal adhesion turnover." in: The Journal of cell biology, Vol. 212, Issue 5, pp. 577-90, (2016) (PubMed).
: "Peroxin Pex14p is the key component for coordinated autophagic degradation of mammalian peroxisomes by direct binding to LC3-II." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 20, Issue 1, pp. 36-49, (2015) (PubMed).
: "ATG12-ATG3 interacts with Alix to promote basal autophagic flux and late endosome function." in: Nature cell biology, Vol. 17, Issue 3, pp. 300-10, (2015) (PubMed).
: "Loss of Atg12, but not Atg5, in pro-opiomelanocortin neurons exacerbates diet-induced obesity." in: Autophagy, Vol. 11, Issue 1, pp. 145-54, (2015) (PubMed).
: "Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. ..." in: Nature cell biology, Vol. 16, Issue 11, pp. 1069-79, (2014) (PubMed).
: "Brain region- and age-dependent dysregulation of p62 and NBR1 in a mouse model of Huntington's disease." in: Neurobiology of disease, Vol. 52, pp. 219-28, (2013) (PubMed).
: "NBR1 acts as an autophagy receptor for peroxisomes." in: Journal of cell science, Vol. 126, Issue Pt 4, pp. 939-52, (2013) (PubMed).
Synonyms and alternative names related to NBR1
neighbor of brca1 gene 1a (nbr1a), neighbor of BRCA1 gene 1 L homeolog (nbr1.L), NBR1, autophagy cargo receptor (NBR1), neighbor of Brca1 gene 1 (Nbr1), NBR1, autophagy cargo receptor (Nbr1), 1A1-3B, Ca125, fa99f08, M17S2, MGC69008, mKIAA0049, NBR1, RGD1311421, wu:fa99f08Protein level used designations for NBR1
- neighbor of BRCA1 gene 1
- next to BRCA1 gene 1 protein
- next to BRCA1 gene 1 protein-like
- cell migration-inducing gene 19 protein
- membrane component chromosome 17 surface marker 2
- membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125)
- migration-inducing protein 19
- neighbor of BRCA1 gene 1 protein
- protein 1A1-3B
- membrane component chromosome 17 surface marker 2 homolog
- next to the Brca1
- ovarian carcinoma antigen CA125
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