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NCBP2 Products

(Nuclear Cap Binding Protein Subunit 2 (NCBP2))
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured NCBP2 Categories

NCBP2 Antibodies

High quality antibodies with extensive validation data.

NCBP2 ELISA Kits

Reliable ELISA kits for a wide range of species.

NCBP2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NCBP2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN6144401
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7074870
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7161752
Quantity 100 μL
Datasheet Datasheet

Recommended NCBP2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648149
Quantity 96 tests
Datasheet Datasheet

Recommended NCBP2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124201
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312086
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312084
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our NCBP2 products

Hallais, Pontvianne, Andersen, Clerici, Lener, Benbahouche, Gostan, Vandermoere, Robert, Cusack, Verheggen, Jensen, Bertrand: "CBC-ARS2 stimulates 3'-end maturation of multiple RNA families and favors cap-proximal processing." in: Nature structural & molecular biology, Vol. 20, Issue 12, pp. 1358-66, (2013) (PubMed).

Yamashita, Izumi, Kashima, Ohnishi, Saari, Katsuhata, Muramatsu, Morita, Iwamatsu, Hachiya, Kurata, Hirano, Anderson, Ohno: "SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay." in: Genes & development, Vol. 23, Issue 9, pp. 1091-105, (2009) (PubMed).

Mazza, Segref, Mattaj, Cusack: "Large-scale induced fit recognition of an m(7)GpppG cap analogue by the human nuclear cap-binding complex." in: The EMBO journal, Vol. 21, Issue 20, pp. 5548-57, (2002) (PubMed).

Calero, Wilson, Ly, Rios-Steiner, Clardy, Cerione: "Structural basis of m7GpppG binding to the nuclear cap-binding protein complex." in: Nature structural biology, Vol. 9, Issue 12, pp. 912-7, (2002) (PubMed).

Synonyms and alternative names related to NCBP2

cap binding protein 20 (Cbp20), nuclear cap binding protein subunit 2 (Ncbp2), nuclear cap binding protein subunit 2 (ncbp2), nuclear cap binding protein subunit 2 (NCBP2), nuclear cap binding protein subunit 2, 20kDa (NCBP2), nuclear cap binding protein subunit 2 L homeolog (ncbp2.L), nuclear cap-binding protein subunit 2 (Cbp20), CAP-binding protein 20 (CBP20), Nuclear cap-binding protein subunit 2 (ncbp-2), 20kDa, 5930413E18Rik, AA536802, AI843301, ATCBP20, C79367, CAP-binding protein 20, CBC2, CBP20, CG12357, CHUNP6917, Dmel\\CG12357, MLN1.12, MLN1_12, Ncbp2, NIP1, zgc:92592

Protein level used designations for NCBP2

  • CG12357-PA
  • Cbp20-PA
  • 20 kDa nuclear cap-binding protein
  • CBP20
  • NCBP 20 kDa subunit
  • nuclear cap binding protein subunit 2, 20kDa
  • nuclear cap-binding protein subunit 2
  • nuclear cap binding protein subunit 2, 20kD
  • NCBP interacting protein 1
  • NCBP-interacting protein 1
  • cell proliferation-inducing gene 55 protein
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