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NCS1 Products

(Neuronal Calcium Sensor 1 (NCS1))

Categories

This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured NCS1 Categories

NCS1 Antibodies

High quality antibodies with extensive validation data.

NCS1 ELISA Kits

Reliable ELISA kits for a wide range of species.

NCS1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NCS1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (3)
  • (3)
Cat. No. ABIN544559
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (3)
Cat. No. ABIN2856122
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7161360
Quantity 100 μL
Datasheet Datasheet

Recommended NCS1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1144849
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1144850
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1144851
Quantity 96 tests
Datasheet Datasheet

Recommended NCS1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124154
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354420
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3084374
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our NCS1 products

De Cotiis, Woll, Fox, Hill, Levenson, Flanagan: "Optimized expression and purification of myristoylated human neuronal calcium sensor 1 in E. coli." in: Protein expression and purification, Vol. 61, Issue 2, pp. 103-12, (2008) (PubMed).

Szafranski, Schindler, Taudien, Hiller, Huse, Jahn, Schreiber, Backofen, Platzer: "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns." in: Genome biology, Vol. 8, Issue 8, pp. R154, (2008) (PubMed).

Kabbani, Levenson: "Antipsychotic-induced alterations in D2 dopamine receptor interacting proteins within the cortex." in: Neuroreport, Vol. 17, Issue 3, pp. 299-301, (2006) (PubMed).

Kabbani, Jeromin, Levenson: "Dynamin-2 associates with the dopamine receptor signalplex and regulates internalization of activated D2 receptors." in: Cellular signalling, Vol. 16, Issue 4, pp. 497-503, (2004) (PubMed).

OCallaghan, Burgoyne: "Identification of residues that determine the absence of a Ca(2+)/myristoyl switch in neuronal calcium sensor-1." in: The Journal of biological chemistry, Vol. 279, Issue 14, pp. 14347-54, (2004) (PubMed).

Koh, Undie, Kabbani, Levenson, Goldman-Rakic, Lidow: "Up-regulation of neuronal calcium sensor-1 (NCS-1) in the prefrontal cortex of schizophrenic and bipolar patients." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 1, pp. 313-7, (2003) (PubMed).

Kabbani, Negyessy, Lin, Goldman-Rakic, Levenson: "Interaction with neuronal calcium sensor NCS-1 mediates desensitization of the D2 dopamine receptor." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 22, Issue 19, pp. 8476-86, (2002) (PubMed).

Burgoyne, Weiss: "The neuronal calcium sensor family of Ca2+-binding proteins." in: The Biochemical journal, Vol. 353, Issue Pt 1, pp. 1-12, (2001) (PubMed).

Bourne, Dannenberg, Pollmann, Marchot, Pongs: "Immunocytochemical localization and crystal structure of human frequenin (neuronal calcium sensor 1)." in: The Journal of biological chemistry, Vol. 276, Issue 15, pp. 11949-55, (2001) (PubMed).

Braunewell, Gundelfinger: "Intracellular neuronal calcium sensor proteins: a family of EF-hand calcium-binding proteins in search of a function." in: Cell and tissue research, Vol. 295, Issue 1, pp. 1-12, (1999) (PubMed).

Synonyms and alternative names related to NCS1

neuronal calcium sensor 1 (NCS1), neuronal calcium sensor 1a (ncs1a), frequenin homolog (freq), neuronal calcium sensor 1 (Ncs1), neuronal calcium sensor 1 (ncs1), neuronal calcium sensor 1 L homeolog (ncs1.L), calcium sensor-1 (cse-1), neuronal calcium sensor 1 (MGYG_03475), calcium-binding protein NCS-1 (PGTG_09250), neuronal calcium sensor 1 (Tsp_06748), Neuronal calcium sensor 1 (ncs1), Neuronal calcium sensor 1 (ncs-1), neuronal calcium sensor 1b (ncs1b), 9430075O15Rik, A730032G13Rik, AI836659, FLUP, flup, FREQ, freq, Freq, freqa, freqb, LOC100189965, Mfreq, MGC75953, NCS-1, wu:fa55b03, xfreq, zgc:63620

Protein level used designations for NCS1

  • frequenin homolog
  • frequenin-like protein
  • neuronal calcium sensor-1
  • putative frequenin
  • frequenin-like ubiquitous protein
  • frequenin homolog a
  • ncs-1a
  • neuronal calcium sensor-1a
  • NCS-1
  • neuronal calcium sensor 1
  • frequenin
  • Neuronal calcium sensor 1
  • neuronal calcium sensor homologue
  • fa55b03
  • frequenin homolog b
  • ncs-1b
  • neuronal calcium sensor-1b
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