NCS1 Protein (AA 1-190) (His tag)
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- Target See all NCS1 Proteins
- NCS1 (Neuronal Calcium Sensor 1 (NCS1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-190
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NCS1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMGKSNSK LKPEVVEELT RKTYFTEKEV QQWYKGFIKD CPSGQLDAAG FQKIYKQFFP FGDPTKFATF VFNVFDENKD GRIEFSEFIQ ALSVTSRGTL DEKLRWAFKL YDLDNDGYIT RNEMLDIVDA IYQMVGNTVE LPEEENTPEK RVDRIFAMMD KNADGKLTLQ EFQEGSKADP SIVQALSLYD GLV
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product NCS1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 30 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- NCS1 (Neuronal Calcium Sensor 1 (NCS1))
- Alternative Name
- NCS1 (NCS1 Products)
- Synonyms
- FREQ Protein, NCS-1 Protein, LOC100189965 Protein, FLUP Protein, freq Protein, freqa Protein, zgc:63620 Protein, 9430075O15Rik Protein, A730032G13Rik Protein, AI836659 Protein, Freq Protein, Mfreq Protein, flup Protein, xfreq Protein, MGC75953 Protein, freqb Protein, wu:fa55b03 Protein, neuronal calcium sensor 1 Protein, neuronal calcium sensor 1a Protein, frequenin homolog Protein, neuronal calcium sensor 1 L homeolog Protein, calcium sensor-1 Protein, calcium-binding protein NCS-1 Protein, Neuronal calcium sensor 1 Protein, neuronal calcium sensor 1b Protein, NCS1 Protein, ncs1a Protein, freq Protein, Ncs1 Protein, ncs1 Protein, ncs1.L Protein, cse-1 Protein, MGYG_03475 Protein, PGTG_09250 Protein, Tsp_06748 Protein, ncs-1 Protein, ncs1b Protein
- Background
- NCS1 is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. This protein regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. It is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human NCS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 24.3. kDa (213aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_055101
- UniProt
- P62166
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