NELL2 Protein (AA 22-238) (His tag)
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- Target See all NELL2 Proteins
- NELL2 (NEL-Like 2 (Chicken) (NELL2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-238
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NELL2 protein is labelled with His tag.
- Application
- Western Blotting (WB), ELISA, Mass Spectrometry (MS), Neutralization (Neut)
- Purity
- ~95 %
- Top Product
- Discover our top product NELL2 Protein
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NEL-Like 2 (Chicken) (NELL2) (AA 1-816) protein (GST tag)
NELL2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
NEL-Like 2 (Chicken) (NELL2) (AA 301-400) protein (GST tag)NELL2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
NEL-Like 2 (Chicken) (NELL2) (AA 22-816) protein (His tag)Crystallography grade NELL2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
NEL-Like 2 (Chicken) (NELL2) (AA 25-819) protein (His tag)Crystallography grade NELL2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
NEL-Like 2 (Chicken) (NELL2) (Transcript Variant 5) protein (Myc-DYKDDDDK Tag)NELL2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- This recombinant protein can be used for WB, ELISA, MS and neutralization assays.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 100 mM sodium phosphate, 10 mM Tris, 500 mM NaCl, 25 mM imidazole, 2 mM MgCl2, 10 % gycerol
- Handling Advice
- Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Storage
- -80 °C
- Storage Comment
- Store in working aliquots at -70 °C.
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- Target
- NELL2 (NEL-Like 2 (Chicken) (NELL2))
- Alternative Name
- NELL2 (NELL2 Products)
- Synonyms
- A330108N19Rik Protein, R75516 Protein, mel91 Protein, nel Protein, NRP2 Protein, nell2 Protein, wu:fj43h11 Protein, zgc:158375 Protein, neural EGFL like 2 L homeolog Protein, NEL-like 2 Protein, neural EGFL like 2 Protein, neural EGFL like 2a Protein, nell2.L Protein, Nell2 Protein, NELL2 Protein, nell2a Protein
- Background
- NELL2 is a neuron-specific thrombospondin-1-like extracellular protein containing six epidermal growth factor-like domains (1). It is highly expressed in the hippocampus in vivo (2) and promotes survival of rat primary cultured neurons through activation of JNK and suppression of ERK (3). As ERK is required for the induction of hippocampal long term potentiation (LTP) and JNK appears to be inhibitory on LTP (4,5), it had been suggested that NELL2 may play a role in synaptic plasticity. More recently, NELL2 has been shown to promote differentiation of motor and sensory neurons and stimulates mitogenesis of dorsal root ganglia in chickens (6).
- Molecular Weight
- 28 kDa (Calculated)
- Gene ID
- 54003
- OMIM
- 2494290
- UniProt
- Q61220
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