anti-Human CD40 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended CD40 Antibody (supplied by: Log in to see )

Antigen
CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) Antibodies
  • Bp50
  • CDW40
  • TNFRSF5
  • p50
  • AI326936
  • GP39
  • HIGM1
  • IGM
  • IMD3
  • T-BAM
  • TRAP
  • Tnfrsf5
  • TNFSF5
  • CD40 molecule
  • CD40 antigen
  • CD40
  • Cd40
Epitope
Center
51
37
36
24
23
22
20
18
8
7
6
5
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
628
278
75
20
15
10
9
6
4
4
3
2
2
1
1
1
1
1
Host
Rabbit
476
189
168
22
6
2
Clonality
Polyclonal
Conjugate
This CD40 antibody is un-conjugated
82
80
46
36
18
15
12
11
10
9
7
6
6
6
6
6
6
6
6
6
6
5
5
4
4
4
4
4
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
539
253
206
182
108
92
83
81
50
32
20
19
13
9
6
6
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
Options
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Catalog No. ABIN2855046
$ 466.18
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
17.5 ABIN786601 Func FACS IHC (p) Mouse IgG1 Log in to see mAb89 10
11.116879 ABIN337317 FACS IHC IHC (fro) IHC (p) IP Mouse IgG2a Log in to see LOB7-6 0
11.116879 ABIN241554 FACS IHC IHC (p) Mouse IgG1, kappa Log in to see HB14 0
10 ABIN3030398 IHC (p) WB Rabbit IgG AA 1-360 Log in to see Polyclonal 0
8.5 ABIN2480305 IHC (fro) FACS IHC (p) IP Mouse IgG2a Log in to see LOB7-6 4
8.5 ABIN786599 Func FACS IHC (p) Mouse IgG1 Log in to see G28-5 4
8.116879 ABIN784060 IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal 0
7 ABIN625924 IHC IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal 0
7 ABIN1804378 FACS ICC IHC IHC (fro) IHC (p) IP Mouse IgG2a Log in to see 0
7 ABIN271944 IHC (p) WB Rabbit Log in to see Polyclonal 0
7 ABIN5574526 IHC (p) WB Rabbit Log in to see Polyclonal 0
7 ABIN5574519 FACS IHC (p) Mouse IgG1 kappa Log in to see HB14 0
7 ABIN5649859 IHC (p) WB Mouse IgG1 Log in to see CL1673 0
5.5 ABIN2480314 IHC (fro) FACS IHC (p) IP Mouse IgG2a Log in to see LOB7-6 4
5.5 ABIN2689245 IHC (fro) FACS IHC (zinc) IHC (p) Mouse IgG1, kappa Log in to see 5C3 2
4 ABIN400699 FACS IHC (p) Mouse IgG1 Log in to see HB14 0
4 ABIN2618532 ELISA FACS Func IHC IHC (p) Mouse IgG1 Log in to see EA-5 0
4 ABIN2618536 FACS IHC IHC (fro) IHC (p) IP Mouse IgG2a Log in to see LOB7-6 0
4 ABIN5960844 ELISA IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
4 ABIN681838 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) Antibodies
Epitope Center
(51), (37), (36), (24), (23), (22), (20), (18), (8), (7), (6), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(628), (278), (75), (20), (15), (10), (9), (6), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(476), (189), (168), (22), (6), (2)
Clonality
Polyclonal
Conjugate This CD40 antibody is un-conjugated
(82), (80), (46), (36), (18), (15), (12), (11), (10), (9), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (5), (4), (4), (4), (4), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(539), (253), (206), (182), (108), (92), (83), (81), (50), (32), (20), (19), (13), (9), (6), (6), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
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Product Details anti-CD40 Antibody

Target Details CD40 Application Details Handling Images
Characteristics Rabbit Polyclonal antibody to CD40 (CD40 Molecule, TNF receptor superfamily member 5)
CD40 antibody
Purification Purified by antigen-affinity chromatography.
Immunogen Recombinant protein encompassing a sequence within the center region of human CD40. The exact sequence is proprietary.
Isotype IgG
Plasmids, Primers & others

Target Details CD40

Product Details anti-CD40 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD40 (CD40 Antibody Abstract)
Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Cellular Localization: Isoform I: Cell membrane, Single-pass type I membrane protein , Isoform II: Secreted
Molecular Weight 31 kDa
Gene ID 958
Pathways NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response

Application Details

Product Details anti-CD40 Antibody Target Details CD40 Handling Images back to top
Application Notes Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
Comment

Positive Control: K562 , THP-1

Restrictions For Research Use only

Handling

Product Details anti-CD40 Antibody Target Details CD40 Application Details Images back to top
Format Liquid
Concentration 0.77 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Images

Product Details anti-CD40 Antibody Target Details CD40 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) (Center) antibody (ABIN2855046) IHC-P Image Immunohistochemical analysis of paraffin-embedded human breast cancer, us...
Western Blotting (WB) image for anti-CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) (Center) antibody (ABIN2855046) WB Image Sample (30 ug of whole cell lysate) A: THP-1 15% SDS PAGE antibody diluted a...