anti-Human CD40 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended CD40 Antibody (supplied by: Log in to see )

Antigen
CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) Antibodies
  • Bp50
  • CDW40
  • TNFRSF5
  • p50
  • 2310042E05Rik
  • C130077D06Rik
  • C87049
  • DCTN-50
  • GMP23-48K
  • RBP50
  • AI326936
  • GP39
  • HIGM1
  • IGM
  • IMD3
  • T-BAM
  • TRAP
  • Tnfrsf5
  • TNFSF5
  • CD40 molecule
  • dynactin 2
  • CD40 antigen
  • CD40
  • Dctn2
  • Cd40
Epitope
C-Term
54
41
37
25
24
22
19
18
11
8
6
5
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
646
311
66
20
14
10
10
6
4
3
2
1
1
1
1
Host
Rabbit
503
213
168
23
6
4
Clonality
Polyclonal
Conjugate
This CD40 antibody is un-conjugated
87
85
50
36
24
21
17
15
14
13
9
9
9
9
9
9
9
8
7
7
7
7
6
6
5
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
580
242
206
158
111
103
102
65
47
34
19
15
13
13
9
6
6
4
3
3
3
3
2
2
2
1
1
1
1
1
1
1
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Catalog No. ABIN784060
$ 368.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.43017 ABIN4293028 IHC IHC (p) IP WB Rabbit Log in to see Polyclonal 1
12.43017 ABIN438055 CyTOF FACS IHC IHC (p) WB Mouse IgG2 Log in to see MM0048-9F21
12.43017 ABIN241554 FACS IHC (p) Mouse IgG1, kappa Log in to see HB14
12.43017 ABIN444833 FACS IHC (p) Mouse IgG1 kappa Log in to see HB14
12.43017 ABIN337317 FACS IHC (fro) IHC (p) IP Mouse IgG2a Log in to see LOB7-6
12.43017 ABIN4293054 IHC IHC (p) Rabbit IgG Log in to see Polyclonal
1 ABIN118631 FACS IHC (fro) IHC (p) IP Mouse IgG2a Log in to see LOB7-6 2
1 ABIN111321 Func FACS IHC (fro) IHC (p) Mouse IgG1 Log in to see MAB89 4
1 ABIN1688355 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN400699 FACS IHC (p) Mouse IgG1 Log in to see HB14
1 ABIN1688347 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN271944 IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN2480305 IHC (fro) FACS IHC (p) IP Mouse IgG2a Log in to see LOB7-6 4
1 ABIN681838 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN2855046 IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
1 ABIN625924 IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN4293056 IHC IHC (p) WB Mouse IgG1 Log in to see CL1673
1 ABIN1732862 IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN2618537 IHC (p) WB Mouse IgG2a AA 21-166 Log in to see 8B8
1 ABIN2618544 IHC (p) WB Mouse IgG2b AA 21-166 Log in to see 9F4

General

Antigen CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) Antibodies
Epitope C-Term
(54), (41), (37), (25), (24), (22), (19), (18), (11), (8), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(646), (311), (66), (20), (14), (10), (10), (6), (4), (3), (2), (1), (1), (1), (1)
Host Rabbit
(503), (213), (168), (23), (6), (4)
Clonality
Polyclonal
Conjugate This CD40 antibody is un-conjugated
(87), (85), (50), (36), (24), (21), (17), (15), (14), (13), (9), (9), (9), (9), (9), (9), (9), (8), (7), (7), (7), (7), (6), (6), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(580), (242), (206), (158), (111), (103), (102), (65), (47), (34), (19), (15), (13), (13), (9), (6), (6), (4), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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Product Details anti-CD40 Antibody

Target Details CD40 Application Details Handling Images
Specificity This antibody reacts to the C-term of CD40.
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Immunoaffinity chromatography
Immunogen CD40 antibody was raised against a synthetic peptide derived from C-terminal of human CD40
Isotype IgG

Target Details CD40

Product Details anti-CD40 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD40 (CD40 Antibody Abstract)
Background CD40 is a member of the TNF-receptor superfamily. It has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this CD40 and serves as a mediator of the signal transduction. The interaction of CD40 and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.Synonyms: B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5
Gene ID 958
NCBI Accession NP_001241
Research Area Stem Cells, Hematopoietic Progenitors, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells, Apoptosis/Necrosis, Inflammation, Cancer
Pathways NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response

Application Details

Product Details anti-CD40 Antibody Target Details CD40 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD40 Antibody Target Details CD40 Application Details Images back to top
Format Liquid
Buffer 10 mM PBS, pH 7.4 containing BSA as stabilizer and sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Images

Product Details anti-CD40 Antibody Target Details CD40 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) (C-Term) antibody (ABIN784060) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)