anti-Rat (Rattus) EGFR antibody for Immunohistochemistry

Recommended EGFR Antibody (supplied by: Log in to see )

Antigen
Epidermal Growth Factor Receptor (EGFR) Antibodies
  • C-erb
  • CG10079
  • D-EGFR
  • D-Egf
  • DEGFR
  • DER
  • DER flb
  • DER/EGFR
  • DER/faint little ball
  • DER/top
  • DER/torpedo
  • DER1
  • DEgfr
  • Degfr
  • Der
  • DmHD-33
  • Dmel\\CG10079
  • EFG-R
  • EGF-R
  • EGFR
  • EGFr
  • EGfr
  • EK2-6
  • Egf
  • Egf-r
  • EgfR
  • El
  • Elp
  • Elp-1
  • Elp-B1
  • Elp-B1RB1
  • HD-33
  • TOP
  • Torpedo/DER
  • Torpedo/Egfr
  • c-erbB
  • d-egf-r
  • dEGFR
  • dEGFR1
  • dEgfr
  • der
  • egfr
  • flb
  • l(2)05351
  • l(2)09261
  • l(2)57DEFa
  • l(2)57EFa
  • l(2)57Ea
  • mor1
  • top
  • top/DER
  • top/flb
  • torpedo/Egfr
  • torpedo/egfr
  • EGFR12
  • EGFR15
  • egfr1
  • Erbb2
  • ERBB
  • ERBB1
  • HER1
  • PIG61
  • mENA
  • ErbB-1
  • Errp
  • 9030024J15Rik
  • AI552599
  • Erbb
  • Errb1
  • Wa5
  • wa-2
  • wa2
  • epidermal growth factor receptor
  • Epidermal growth factor receptor
  • epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
  • EGFR
  • Egfr
  • egfra
  • egfr1
  • LOC5564544
Epitope
pSer1071
117
84
66
62
60
57
56
55
52
51
50
37
36
35
33
32
30
29
28
25
25
25
22
18
18
18
18
17
16
15
15
15
15
15
15
15
14
14
13
11
10
8
8
8
7
6
6
6
6
6
6
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
2415
843
714
29
27
20
19
16
14
7
4
3
2
2
2
2
2
2
2
1
1
1
1
Host
Rabbit
1504
835
72
21
14
5
2
1
1
Clonality
Polyclonal
Conjugate
This EGFR antibody is un-conjugated
93
69
65
61
52
41
40
29
25
21
20
20
20
20
18
18
18
18
18
18
18
18
17
17
17
17
17
16
15
8
8
8
8
8
8
8
8
8
8
8
8
8
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
1511
663
619
592
453
393
250
234
125
89
86
54
53
40
22
21
19
11
9
8
7
4
4
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN6256098
$ 390.77
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
21.990124 ABIN6255471 ELISA ICC IF IHC WB Rabbit IgG pSer695 Log in to see Polyclonal 0
21.990124 ABIN6254923 ELISA ICC IF IHC WB Rabbit IgG pSer1026 Log in to see Polyclonal 0
21.990124 ABIN6261461 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0
21.990124 ABIN1872454 IHC WB Rabbit IgG Log in to see Polyclonal 0
18.990124 ABIN6256596 ELISA ICC IF IHC WB Rabbit IgG pThr693 Log in to see Polyclonal 0
18.990124 ABIN6256611 ELISA ICC IF IHC WB Rabbit IgG pTyr1016 Log in to see Polyclonal 0
18.990124 ABIN6290331 IHC WB Rabbit IgG Log in to see Polyclonal 0
18.990124 ABIN6290334 IF IHC WB Rabbit IgG Log in to see Polyclonal 0
18.275578 ABIN3181990 ELISA IHC WB Rabbit IgG pTyr1197 Log in to see Polyclonal 0
18.275578 ABIN3184422 ELISA IF IHC WB Rabbit IgG Ser315 Log in to see Polyclonal 0
18.275578 ABIN3184431 ELISA IF IHC WB Rabbit IgG Ser325 Log in to see Polyclonal 0
17.5 ABIN6261462 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 1
16.775578 ABIN966039 IHC Rabbit pTyr869 Log in to see 6
16.775578 ABIN966037 IHC Rabbit pTyr1172 Log in to see 5
16.775578 ABIN966034 IHC Rabbit pThr693 Log in to see 4
16.775578 ABIN966032 IHC Rabbit pSer1070 Log in to see 4
16.775578 ABIN966033 IHC Rabbit pThr678 Log in to see 4
16.775578 ABIN966038 IHC Rabbit pTyr1197 Log in to see 4
16.775578 ABIN966035 IHC Rabbit pTyr1092 Log in to see 5
16.775578 ABIN966041 IHC Rabbit Log in to see Polyclonal 5

General

Antigen Epidermal Growth Factor Receptor (EGFR) Antibodies
Epitope pSer1071
(117), (84), (66), (62), (60), (57), (56), (55), (52), (51), (50), (37), (36), (35), (33), (32), (30), (29), (28), (25), (25), (25), (22), (18), (18), (18), (18), (17), (16), (15), (15), (15), (15), (15), (15), (15), (14), (14), (13), (11), (10), (8), (8), (8), (7), (6), (6), (6), (6), (6), (6), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(2415), (843), (714), (29), (27), (20), (19), (16), (14), (7), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Host Rabbit
(1504), (835), (72), (21), (14), (5), (2), (1), (1)
Clonality
Polyclonal
Conjugate This EGFR antibody is un-conjugated
(93), (69), (65), (61), (52), (41), (40), (29), (25), (21), (20), (20), (20), (20), (18), (18), (18), (18), (18), (18), (18), (18), (17), (17), (17), (17), (17), (16), (15), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(1511), (663), (619), (592), (453), (393), (250), (234), (125), (89), (86), (54), (53), (40), (22), (21), (19), (11), (9), (8), (7), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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Product Details anti-EGFR Antibody

Target Details EGFR Application Details Handling Images
Specificity Phospho-EGFR (Ser1071) Antibody detects endogenous levels of EGFR only when phosphorylated at Serine 1071
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Immunogen A synthesized peptide derived from human EGFR around the phosphorylation site of Serine 1071
Isotype IgG
Plasmids, Primers & others

Target Details EGFR

Product Details anti-EGFR Antibody Application Details Handling Images back to top
Antigen
Alternative Name EGFR (EGFR Antibody Abstract)
Background

Description: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF (PubMed:2790960, PubMed:7679104, PubMed:8144591, PubMed:9419975, PubMed:15611079, PubMed:12297049, PubMed:27153536, PubMed:20837704). Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules (PubMed:27153536). May also activate the NF-kappa-B signaling cascade (PubMed:11116146). Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling (PubMed:11602604). Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin (PubMed:11483589). Plays a role in enhancing learning and memory performance (By similarity).

Gene: EGFR

Molecular Weight 150-160kDa
Gene ID 1956
UniProt P00533
Pathways NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation

Application Details

Product Details anti-EGFR Antibody Target Details EGFR Handling Images back to top
Application Notes WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
Restrictions For Research Use only

Handling

Product Details anti-EGFR Antibody Target Details EGFR Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months

Images

Product Details anti-EGFR Antibody Target Details EGFR Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Epidermal Growth Factor Receptor (EGFR) (pSer1071) antibody (ABIN6256098) ABIN6267269 at 1/100 staining rat lung tissue sections by IHC-P. The tissue was forma...
Immunohistochemistry (IHC) image for anti-Epidermal Growth Factor Receptor (EGFR) (pSer1071) antibody (ABIN6256098) ABIN6267269 at 1/100 staining mouse gastric tissue sections by IHC-P. The tissue was ...
Immunohistochemistry (IHC) image for anti-Epidermal Growth Factor Receptor (EGFR) (pSer1071) antibody (ABIN6256098) ABIN6267269 at 1/100 staining rat uterine tissue sections by IHC-P. The tissue was fo...
Immunohistochemistry (IHC) image for anti-Epidermal Growth Factor Receptor (EGFR) (pSer1071) antibody (ABIN6256098) ABIN6267269 at 1/100 staining human heart tissue sections by IHC-P. The tissue was fo...
Immunohistochemistry (IHC) image for anti-Epidermal Growth Factor Receptor (EGFR) (pSer1071) antibody (ABIN6256098) ABIN6267269 at 1/100 staining human appendiceal tissue sections by IHC-P. The tissue ...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Epidermal Growth Factor Receptor (EGFR) (pSer1071) antibody (ABIN6256098) ABIN6267269 staining SK-OV3 by IF/ICC. The sample were fixed with PFA and permeabiliz...
Western Blotting (WB) image for anti-Epidermal Growth Factor Receptor (EGFR) (pSer1071) antibody (ABIN6256098) Western blot analysis of EGFR phosphorylation expression in serum treated HepG2 whole...
Western Blotting (WB) image for anti-Epidermal Growth Factor Receptor (EGFR) (pSer1071) antibody (ABIN6256098) Western blot analysis of Phospho-EGFR (Ser1071) expression in various lysates