|Antigen||Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) Antibodies|
|Epitope||AA 127-309 Alternatives|
|Reactivity||Mouse (Murine) Alternatives|
|Conjugate||This TNFSF13B antibody is un-conjugated Alternatives|
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Western Blotting (WB)
|6 references available|
|Supplier||Log in to see|
Product Details anti-TNFSF13B AntibodyTarget Details TNFSF13B Application Details Handling References for anti-TNFSF13B antibody (ABIN4899233) Images
|Specificity||Detects mouse BAFF in direct ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant mouse (rm) 4-1BB Ligand, rmEDA, rmFas Ligand, rmOX40 Ligand, rmTNF-alpha , rmTRANCE, rmTWEAK, recombinant human (rh) APRIL, rhBAFF, rhEDA-A2, rhGITR Ligand, rhLIGHT, rhLymphotoxin alpha 1/beta 2, rhLymphotoxin alpha 2/beta 1, rhTNF-alpha , rhTRAIL, rhVEGI, recombinant canine, cotton rat, equine, feline, porcine, or rat TNF-alpha .|
|Purification||Protein A or G purified from hybridoma culture supernatant|
|Sterility||0.2 μm filtered|
|Immunogen||Mouse myeloma cell line NS0-derived recombinant mouse BAFF, Ala127-Leu309, Accession # Q9WU72|
|Plasmids, Primers & others|
Target Details TNFSF13BProduct Details anti-TNFSF13B Antibody Application Details Handling References for anti-TNFSF13B antibody (ABIN4899233) Images back to top
|Alternative Name||BAFF/BLyS (TNFSF13B Antibody Abstract)|
|Background||Alternative Names: ApoL related ligand TALL-1, B lymphocyte stimulator, BAFFB-cell activating factor, B-cell-activating factor, BLyS, BLYSB-lymphocyte stimulator, CD257, CD257 antigen, Dendritic cell-derived TNF-like molecule, DTL, TALL1, TALL-1delta BAFF, TALL1Delta4 BAFF, THANK, TNF and ApoL-related leukocyte expressed ligand 1, TNF- and APOL-related leukocyte expressed ligand 1, TNF homolog that activates apoptosis, TNFSF13B, TNFSF20, tumor necrosis factor (ligand) superfamily, member 13b, tumor necrosis factor (ligand) superfamily, member 20, tumor necrosis factor ligand superfamily member 13B, tumor necrosis factor superfamily, member 13b, tumor necrosis factor-like protein ZTNF4, ZTNF4|
|Pathways||NF-kappaB Signaling, Production of Molecular Mediator of Immune Response|
Application DetailsProduct Details anti-TNFSF13B Antibody Target Details TNFSF13B Handling References for anti-TNFSF13B antibody (ABIN4899233) Images back to top
Western Blot 1 μg/mL
Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells
|Restrictions||For Research Use only|
HandlingProduct Details anti-TNFSF13B Antibody Target Details TNFSF13B Application Details References for anti-TNFSF13B antibody (ABIN4899233) Images back to top
|Reconstitution||Reconstitute at 0.5 mg/mL in sterile PBS.|
|Buffer||Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.|
|Storage||4 °C,-20 °C,-80 °C|
|Storage Comment||Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.|
|Expiry Date||12 months|
References for anti-TNFSF13B antibody (ABIN4899233)Product Details anti-TNFSF13B Antibody Target Details TNFSF13B Application Details Handling Images back to top
|Product cited in:||
Yasuda, Watkins, Kochar, Wilson, Laskow, Richez, Bonegio, Rifkin: "Interferon regulatory factor-5 deficiency ameliorates disease severity in the MRL/lpr mouse model of lupus in the absence of a mutation in DOCK2." in: PLoS ONE, Vol. 9, Issue 7, pp. e103478, 2014 Method employed by authors: ELISA (Capture) (ELISA (Capture)) (Sample species: Mouse (Murine)).
Giordano, Draves, Li, Hohl, Clark: "Nitric oxide regulates BAFF expression and T cell-independent antibody responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 3, pp. 1110-20, 2014 Method employed by authors: Flow Cytometry (FACS) (Sample species: Mouse (Murine)).
Kanagavelu, Termini, Gupta, Raffa, Fuller, Rivas, Philip, Kornbluth, Stone: "HIV-1 adenoviral vector vaccines expressing multi-trimeric BAFF and 4-1BBL enhance T cell mediated anti-viral immunity." in: PLoS ONE, Vol. 9, Issue 2, pp. e90100, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Human).
Scapini, Hu, Chu, Migone, Defranco, Cassatella, Lowell: "Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice." in: The Journal of experimental medicine, Vol. 207, Issue 8, pp. 1757-73, 2010 Method employed by authors: ELISA (ELISA) (Sample species: Mouse (Murine)).
Parameswaran, Ben David, Sharabi, Zinger, Mozes: "B-cell activating factor (BAFF) plays a role in the mechanism of action of a tolerogenic peptide that ameliorates lupus." in: Clinical immunology (Orlando, Fla.), Vol. 131, Issue 2, pp. 223-32, 2009 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).
Wan, Zhou, Duan, Morel: "Direct B cell stimulation by dendritic cells in a mouse model of lupus." in: Arthritis and rheumatism, Vol. 58, Issue 6, pp. 1741-50, 2008 Method employed by authors: Flow Cytometry (FACS) (Sample species: Mouse (Murine)).