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|Antigen||Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) Antibodies|
|Epitope||AA 254-269 Alternatives|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This TNFSF13B antibody is un-conjugated Alternatives|
Immunofluorescence (IF), Western Blotting (WB)
|1 reference available|
|Supplier||Log in to see|
Product Details anti-TNFSF13B AntibodyTarget Details TNFSF13B Application Details Handling References for anti-TNFSF13B antibody (ABIN319035) Images
|Specificity||This antibody recognises CD257 (also known as BLyS, BAFF, TALL-1 and THANK).|
|Immunogen||Peptide corresponding to amino acids 254-269 of human CD257 (BAFF).|
Target Details TNFSF13BProduct Details anti-TNFSF13B Antibody Application Details Handling References for anti-TNFSF13B antibody (ABIN319035) Images back to top
|Alternative Name||CD257 / BAFF (TNFSF13B Antibody Abstract)|
|Background||CD257 is a novel member of the tumor necrosis factor (TNF) superfamily. CD257 and its receptor TACI/BCMA are involved in the development of autoimmune diseases. CD257 has been shown to activate NFkB and JNK (c-jun N-terminal kinase) and induce apoptosis.Synonyms: B cell-activating factor, B lymphocyte stimulator, BAFF, BLYS, Dendritic cell-derived TNF-like molecule, TALL1, TNF- and APOL-related leukocyte expressed ligand 1, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13B, ZTNF4|
|Pathways||NF-kappaB Signaling, Production of Molecular Mediator of Immune Response|
Application DetailsProduct Details anti-TNFSF13B Antibody Target Details TNFSF13B Handling References for anti-TNFSF13B antibody (ABIN319035) Images back to top
Western Blot: 0.25g/mL - 1g/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-TNFSF13B Antibody Target Details TNFSF13B Application Details References for anti-TNFSF13B antibody (ABIN319035) Images back to top
|Buffer||Phosphate buffered saline containing 0.02 % Sodium Azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
References for anti-TNFSF13B antibody (ABIN319035)Product Details anti-TNFSF13B Antibody Target Details TNFSF13B Application Details Handling Images back to top
Moore, Belvedere, Orr, Pieri, LaFleur, Feng, Soppet, Charters, Gentz, Parmelee, Li, Galperina, Giri, Roschke, Nardelli, Carrell, Sosnovtseva, Greenfield, Ruben, Olsen, Fikes, Hilbert: "BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator." in: Science (New York, N.Y.), Vol. 285, Issue 5425, pp. 260-3, 1999
ImagesProduct Details anti-TNFSF13B Antibody Target Details TNFSF13B Application Details Handling References for anti-TNFSF13B antibody (ABIN319035) back to top