NSUN2 Products
(NOP2/Sun Domain Family, Member 2 (NSUN2))
Categories
This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2011].
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Featured NSUN2 Categories
NSUN2 Antibodies
High quality antibodies with extensive validation data.
NSUN2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NSUN2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN1681117
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7173496
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6263746
Quantity
100 μL
Datasheet
Datasheet
Recommended NSUN2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6231553
Quantity
96 tests
Datasheet
Datasheet
Recommended NSUN2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3094279
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3134928
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2727652
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our NSUN2 products
: "Stem cell function and stress response are controlled by protein synthesis." in: Nature, Vol. 534, Issue 7607, pp. 335-40, (2016) (PubMed).: "Nuclear envelope-associated endosomes deliver surface proteins to the nucleus." in: Nature communications, Vol. 6, pp. 8218, (2015) (PubMed).
: "SUN2 exerts tumor suppressor functions by suppressing the Warburg effect in lung cancer." in: Scientific reports, Vol. 5, pp. 17940, (2015) (PubMed).
: "The mouse cytosine-5 RNA methyltransferase NSun2 is a component of the chromatoid body and required for testis differentiation." in: Molecular and cellular biology, Vol. 33, Issue 8, pp. 1561-70, (2013) (PubMed).
: "A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton." in: The Journal of cell biology, Vol. 202, Issue 7, pp. 1023-39, (2013) (PubMed).
: "BRD4 short isoform interacts with RRP1B, SIPA1 and components of the LINC complex at the inner face of the nuclear membrane." in: PLoS ONE, Vol. 8, Issue 11, pp. e80746, (2013) (PubMed).
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
: "Mutation in NSUN2, which encodes an RNA methyltransferase, causes autosomal-recessive intellectual disability." in: American journal of human genetics, Vol. 90, Issue 5, pp. 856-63, (2012) (PubMed).
: "The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate." in: PLoS genetics, Vol. 7, Issue 12, pp. e1002403, (2011) (PubMed).
: "Samp1 is functionally associated with the LINC complex and A-type lamina networks." in: Journal of cell science, Vol. 124, Issue Pt 12, pp. 2077-85, (2011) (PubMed).
Synonyms and alternative names related to NSUN2
NOL1/NOP2/Sun domain family member 2 (Nsun2), NOP2/Sun RNA methyltransferase family member 2 (NSUN2), NOP2/Sun RNA methyltransferase family, member 2 (Nsun2), NOP2/Sun RNA methyltransferase family member 2 S homeolog (nsun2.S), D13Wsu123e, Misu, MISU, MRT5, RGD1311954, SAKI, TRM4Protein level used designations for NSUN2
- Myc-induced SUN domain containing protein
- NOL1/NOP2/Sun domain family 2
- myc-induced SUN domain-containing protein
- tRNA (cytosine(34)-C(5))-methyltransferase
- tRNA (cytosine-5-)-methyltransferase NSUN2
- NOL1/NOP2/Sun domain family, member 2
- NOP2/Sun domain family, member 2
- 5-methycytoisine methyltransferase
- Myc-induced SUN-domain-containing protein
- NOL1/NOP2/Sun domain family member 2
- hTrm4
- substrate of AIM1/Aurora kinase B
- tRNA methyltransferase 4 homolog
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