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anti-Human Androgen Receptor Antibodies:
anti-Mouse (Murine) Androgen Receptor Antibodies:
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Human Monoclonal Androgen Receptor Primary Antibody for IHC (p), IHC - ABIN252555
Lin, Hu, Yang, Altuwaijri, Chen, Kang, Chang: Suppression versus induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers. in The Journal of biological chemistry 2003
Show all 12 Pubmed References
Human Polyclonal Androgen Receptor Primary Antibody for ICC, IHC (p) - ABIN3044419
Xiang-Yun, Ying-Wen, Chen-Jing, Jiu-Jiu, Qi, Bo, Zu-Yue: Possible mechanism of benign prostatic hyperplasia induced by androgen-estrogen ratios in castrated rats. in Indian journal of pharmacology 2011
Show all 7 Pubmed References
Human Monoclonal Androgen Receptor Primary Antibody for IHC, ELISA - ABIN1724724
Tillman, Yuan, Gu, Fazli, Ghosh, Flynt, Gleave, Rennie, Kasper: DJ-1 binds androgen receptor directly and mediates its activity in hormonally treated prostate cancer cells. in Cancer research 2007
Show all 3 Pubmed References
Human Monoclonal Androgen Receptor Primary Antibody for ELISA, WB - ABIN968966
Lindström, Wiklund, Adami, Bälter, Adolfsson, Grönberg: Germ-line genetic variation in the key androgen-regulating genes androgen receptor, cytochrome P450, and steroid-5-alpha-reductase type 2 is important for prostate cancer development. in Cancer research 2006
Show all 2 Pubmed References
Human Monoclonal Androgen Receptor Primary Antibody for ELISA, WB - ABIN965588
Zong, Chi, Wang, Yang, Zhang, Chen, Jiang, Li, Hong, Wang, Yun, Gu: Cyclin D3/CDK11p58 complex is involved in the repression of androgen receptor. in Molecular and cellular biology 2007
Show all 2 Pubmed References
Human Monoclonal Androgen Receptor Primary Antibody for IHC (f), IHC (fro) - ABIN2688843
Fuller: The steroid receptor superfamily: mechanisms of diversity. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1992
Show all 2 Pubmed References
Human Polyclonal Androgen Receptor Primary Antibody for IF (p), IHC (p) - ABIN725240
Madka, Mohammed, Li, Zhang, Biddick, Patlolla, Lightfoot, Towner, Wu, Steele, Kopelovich, Rao: Targeting mTOR and p53 Signaling Inhibits Muscle Invasive Bladder Cancer In Vivo. in Cancer prevention research (Philadelphia, Pa.) 2016
Human Polyclonal Androgen Receptor Primary Antibody for ChIP, ELISA - ABIN250260
Trapman, Klaassen, Kuiper, van der Korput, Faber, van Rooij, Geurts van Kessel, Voorhorst, Mulder, Brinkmann: Cloning, structure and expression of a cDNA encoding the human androgen receptor. in Biochemical and biophysical research communications 1988
Human Monoclonal Androgen Receptor Primary Antibody for CyTOF, FACS - ABIN4900460
Rode, Boehm: Regenerative capacity of adult cortical thymic epithelial cells. in Proceedings of the National Academy of Sciences of the United States of America 2012
Study indicates that both mRNA and protein level of AR increase during prostate cancer (PCa (show FLVCR1 Antibodies)) progression. These levels are even higher in metastatic PCa (show FLVCR1 Antibodies). Further data suggest that elevation of AR may promote PCa (show FLVCR1 Antibodies) metastasis by induction of EMT (show ITK Antibodies) and reduction of KAT5 (show KAT5 Antibodies).
This study aimed to determine the presence and localization of oestrogen receptors (ERs), progesterone receptors (PRs), and androgen receptors (ARs (show SLURP1 Antibodies)) in both healthy and varicose vein wall cells and their relationship with gender.
These findings suggest that CDK11 (show CDK11B Antibodies) is involved in the regulation of AR pathway and AR can be a potential novel prognostic marker and therapeutic target for osteosarcoma treatment.
We use CPRC prostate cancer model and demonstrate that endothelial cells secrete large amount of CCL5 and induces autophagy by suppressing AR expression in prostate cancer cell lines. Consequently, elevated autophagy accelerates focal adhesions proteins disassembly and promoted prostate cancer invasion. Inhibition of both CCL5/CCR5 signaling and autophagy significantly reduces metastasis in vivo
The AR polymorphism is associated with POR (show POR Antibodies) risk, patients with repeats greater than 22 show a higher risk. Our data suggest that AR genotype could play a role in natural ovarian aging.
In all, these data suggest that Aurora A (show AURKA Antibodies) plays a pivotal role in regulation of Androgen receptor variant 7 expression and represents a new therapeutic target in castrate-resistant prostate cancer.
The meta-analysis showed that short CAG and GGN (show GGN Antibodies) repeats in androgen receptor gene were associated with increased risk of prostate cancer, especially in Caucasians.
Knockdown of beta-Klotho (show KLB Antibodies) produced the opposite effects. In conclusion, beta-Klotho (show KLB Antibodies) inhibits EMT (show ITK Antibodies) and plays a tumorsuppressive role in prostate cancer (PCa (show FLVCR1 Antibodies)) , linking FGF/FGFR (show FGFR2 Antibodies)/beta-Klotho (show KLB Antibodies) signaling to the regulation of PCa (show FLVCR1 Antibodies) progression.
The interaction of AR and SP1 (show PSG1 Antibodies) contributes to regulate EPHA3 (show EPHA3 Antibodies) expression.
DHX15 (show DHX15 Antibodies) regulates androgen receptor (AR) activity by modulating E3 ligase Siah2 (show SIAH2 Antibodies)-mediated AR ubiquitination independent of its ATPase (show DNAH8 Antibodies) activity promoting prostate cancer progression.
Here, the authors show that ERG (show ERG Antibodies), through its physical interaction with androgen receptor, induces AR aggregation and endoplasmic reticulum stress in the prostate glands of ERG (show ERG Antibodies) transgenic mice.
CSN6 (show COPS6 Antibodies) and Rab34 (show RAB34 Antibodies) are involved in AR trafficking by regulating the phosphorylation signaling pathway. These findings provide new insights into the testosterone signaling pathway in Sertoli cells that mediates spermatogenesis.
Results provide evidence that androgen receptor is expressed from prenatal stages in mouse heart, supporting the proposition that androgens could be involved in mammalian heart development.
The role of ERbeta (show ESR2 Antibodies) in opposing AR signaling, proliferation, and inflammation suggests that ERbeta (show ESR2 Antibodies)-selective agonists may be used to prevent progression of prostate cancer, prevent fibrosis and development of benign prostatic hyperplasia, and treat prostatitis.
androgen receptor has a central role in the spontaneous regeneration of myelin
Data (including data from studies using transgenic/knockout mice) suggest that AR in insulin (show INS Antibodies)-secreting cells is involved in insulin (show INS Antibodies) secretion and inflammation; AR-deficient insulin (show INS Antibodies)-secreting cells exhibit altered expression of genes involved in inflammation and insulin (show INS Antibodies) secretion demonstrating importance of androgen action in functions of insulin (show INS Antibodies)-secreting cells.
Cyclic mechanical stretch modulated the proliferation of C2C12 cells, which may be attributed to the alterations of AR via IGF-1 (show IGF1 Antibodies)-PI3K/Akt (show AKT1 Antibodies) and IGF-1 (show IGF1 Antibodies)-MAPK (p38 (show MAPK1 Antibodies), ERK1/2) pathways in C2C12 cells.
We show AR expressed in cancer-associated fibroblasts (CAFs) contributes to the tumor-promoting abilities that CAFs exert on epithelial prostate cancer cells. Further, we found that decreased AR expression in CAFs is also associated with an increase in stem cell marker gene expression in prostate cancer epithelial cells.
in clear cell renal cell carcinoma (show MOK Antibodies), enhances lung and liver metastases, while suppressing lymphatic metastasis
Glandular epithelial AR inactivation (with persistent stromal AR action) enhanced PTEN deletion-induced uterine pathology possibly by downregulating progesterone receptor (show PGR Antibodies) expression in the uterus.
substantial up-regulation of androgen receptor expression during trophoblast giant cell differentiation suggests that androgens may be related to this process and are active products of bovine placental steroidogenesis
no association between the AR CAG polymorphism and the relative risk of prostate cancer in white Brazilian individuals with a CAG repeat (show CELF3 Antibodies)
FSHR (show FSHR Antibodies) is specifically regulated through androgen receptor in granulosa cells
Roles of IGF-I (show IGF1 Antibodies) and the estrogen, androgen and IGF-I (show IGF1 Antibodies) receptors in estradiol-17beta- and trenbolone acetate-stimulated proliferation of cultured bovine satellite cells.
In GD20 and PD2 (show PAF1 Antibodies) males we found the reduction of the luminal compartment, inflammatory changes, decreased androgen receptor and increased Cx43 (show GJA1 Antibodies) expression
Data suggest that signal transduction involving androgen receptor is involved in apoptosis of granulosa cells (as seen in follicular atresia).
Pig ejaculated spermatozoa express androgen receptor.
Androgen receptor (AR) and Wilms' tumor gene 1 expression dramatically decreased after heat treatment in Sertoli cells
Zebrafish males lacking the androgen receptor courted females significantly less, showing reduced levels of stereotypic behaviors. Consistent with previous studies, disrupting androgen mechanisms can lead to behavioral changes with potential fitness consequences.
Sertoli cell maturation during puberty in the stallion was accompanied by a reduced expression of anti-Mullerian hormone (show AMH Antibodies) and its receptor, arrest of cell proliferation, increased expression of androgen receptor
The vesicular gland of castrated goats showed significantly lower AR and COX-2 (show COX2 Antibodies) immuno-expression than intact goats indicating that both AR and COX-2 (show COX2 Antibodies) are androgen dependent.
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described.
androgen nuclear receptor variant 2
, dihydrotestosterone receptor
, nuclear receptor subfamily 3 group C member 4
, testicular feminization
, androgen receptor (Testicular feminization), same as Tfm
, androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)
, androgen receptor AR
, Ar beta
, androgen receptor
, prostate androgen receptor