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anti-Human Androgen Receptor Antibodies:
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Human Monoclonal Androgen Receptor Primary Antibody for IHC (p), IHC - ABIN252555
Lin, Hu, Yang, Altuwaijri, Chen, Kang, Chang: Suppression versus induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers. in The Journal of biological chemistry 2003
Show all 12 Pubmed References
Human Monoclonal Androgen Receptor Primary Antibody for IHC (fro), IP - ABIN967444
Chang, Wang, DeLuca, Ross, Shih: Characterization of human androgen receptor overexpressed in the baculovirus system. in Proceedings of the National Academy of Sciences of the United States of America 1992
Show all 6 Pubmed References
Human Monoclonal Androgen Receptor Primary Antibody for IHC, ELISA - ABIN1724724
Tillman, Yuan, Gu, Fazli, Ghosh, Flynt, Gleave, Rennie, Kasper: DJ-1 binds androgen receptor directly and mediates its activity in hormonally treated prostate cancer cells. in Cancer research 2007
Show all 3 Pubmed References
Human Polyclonal Androgen Receptor Primary Antibody for ICC, IHC (p) - ABIN3044419
Xiang-Yun, Ying-Wen, Chen-Jing, Jiu-Jiu, Qi, Bo, Zu-Yue: Possible mechanism of benign prostatic hyperplasia induced by androgen-estrogen ratios in castrated rats. in Indian journal of pharmacology 2011
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Human Monoclonal Androgen Receptor Primary Antibody for ELISA, WB - ABIN968966
Lindström, Wiklund, Adami, Bälter, Adolfsson, Grönberg: Germ-line genetic variation in the key androgen-regulating genes androgen receptor, cytochrome P450, and steroid-5-alpha-reductase type 2 is important for prostate cancer development. in Cancer research 2006
Show all 2 Pubmed References
Human Monoclonal Androgen Receptor Primary Antibody for ELISA, WB - ABIN965588
Zong, Chi, Wang, Yang, Zhang, Chen, Jiang, Li, Hong, Wang, Yun, Gu: Cyclin D3/CDK11p58 complex is involved in the repression of androgen receptor. in Molecular and cellular biology 2007
Show all 2 Pubmed References
Human Monoclonal Androgen Receptor Primary Antibody for IHC (f), IHC (fro) - ABIN2688843
Fuller: The steroid receptor superfamily: mechanisms of diversity. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1992
Show all 2 Pubmed References
Human Monoclonal Androgen Receptor Primary Antibody for CyTOF, FACS - ABIN4900460
Rode, Boehm: Regenerative capacity of adult cortical thymic epithelial cells. in Proceedings of the National Academy of Sciences of the United States of America 2012
Human Polyclonal Androgen Receptor Primary Antibody for ChIP, ELISA - ABIN250260
Trapman, Klaassen, Kuiper, van der Korput, Faber, van Rooij, Geurts van Kessel, Voorhorst, Mulder, Brinkmann: Cloning, structure and expression of a cDNA encoding the human androgen receptor. in Biochemical and biophysical research communications 1988
Human Polyclonal Androgen Receptor Primary Antibody for IF (p), IHC (p) - ABIN725240
Madka, Mohammed, Li, Zhang, Biddick, Patlolla, Lightfoot, Towner, Wu, Steele, Kopelovich, Rao: Targeting mTOR and p53 Signaling Inhibits Muscle Invasive Bladder Cancer In Vivo. in Cancer prevention research (Philadelphia, Pa.) 2016
Within an institutional cohort, the RNA ISH (show ANTXR2 Antibodies) assay identified AR-V7 within FFPE tissue and may have prognostic value in metastatic castration-sensitive prostate cancer. These preliminary findings warrant further study in larger cohorts.
increases hematogenous metastasis (show MOK Antibodies)yet decreases lymphatic metastasis of renal cell carcinoma through differential regulation of VEGF-A vs. VEGF-C via miR-185-5p
Data show that enzalutamide resistance was accompanied by increased androgen receptor (AR) mRNA and protein expression as well as AR gene amplification.
Lipocalin 2 (show LCN2 Antibodies) could facilitate proliferation of castration-resistant prostate cancer cells by activating androgen receptor transcriptional activity.
Tumor cell clusters were more prevalent and bigger in bone marrow aspirates than in blood, expressed higher levels of the androgen receptor protein per tumor cell, and were prognostic in metastatic castration-resistant prostate cancer
Plasma androgen receptor mutational status assessment identifies castration-resistant prostate cancer patients with worse outcome to enzalutamide or abiraterone.
In a 46,XY phenotypically female patient bearing testes in inguinal canal, and diagnosed with complete androgen insensitivity syndrome, the dysfunctioning of AR by mutation enhanced AMH (show AMH Antibodies) expression which ultimately leads to the failure in maturation of Sertoli cells.
increased Snail (show SNAI1 Antibodies) expression during progression to metastatic disease may prime cells for resistance to AR-targeted therapies by promoting AR activity in prostate cancer
lower expression of androgen receptor is associated with more aggressive tumour phenotype and a higher metastatic potential of hepatocellular carcinoma
This mini review focuses on the androgen receptor gene, its link with classical endocrine disruptors and smoking, and how common genetic variants in the androgen receptor gene may influence physiological outcomes.
in clear cell renal cell carcinoma (show MOK Antibodies), enhances lung and liver metastases, while suppressing lymphatic metastasis
Glandular epithelial AR inactivation (with persistent stromal AR action) enhanced PTEN (show PTEN Antibodies) deletion-induced uterine pathology possibly by downregulating progesterone receptor (show PGR Antibodies) expression in the uterus.
CDK2 (show CDK2 Antibodies) phosphorylates polyQ-AR specifically at Ser (show SIGLEC1 Antibodies)(96). Phosphorylation of polyQ-AR by CDK2 (show CDK2 Antibodies) increased protein stabilization and toxicity and is negatively regulated by the adenylyl cyclase/protein kinase A signaling pathway in spinobulbar muscular atrophy.
experimental manipulation of the prenatal androgen level, by blocking the androgen receptor with flutamide or activating the androgen receptor with dihydrotestosterone (DHT), leads to changes in the length of the fingers of all paws in males and females.
Silencing of androgen receptor rescues the muscular spinal atrophy transgenic mice.
Taken together, our findings provide evidence for a novel crosstalk and a crossregulation between ING1 and ING2 in regulating androgen receptor-mediated transactivation and suggest that ING2 acts as a novel corepressor that inhibits AR signaling, prostate cancer cell growth, and migration.
Prostate 5aR1 levels were positively correlated with adjusted prostate most severe lesion scores. Downregulation of androgen receptor and 5alpha-reductase 2, along with upregulation of 5a-reductase 1 in tumors may promote prostatic intraepithelial neoplasia and prostate cancer development in TRAMP (show DPT Antibodies) mice
Bisphenol A inhibits Sertoli cell proliferation by interfering with androgen receptor signaling pathway.
Findings indicate that targeting androgen receptor (AR) with ASC (show STS Antibodies)-J9 in experimental autoimmune myocarditis (EAM) resulted in an attenuation in the severity of disease and cardiac injury.
The findings suggest that Cyp3a deficiency stimulated the expression of Scap via activation of the AR, which elevated cholesterogenic gene expression levels through activation of SREBP2 (show SREBF2 Antibodies) and increased total cholesterol contents in the prostate.
substantial up-regulation of androgen receptor expression during trophoblast giant cell differentiation suggests that androgens may be related to this process and are active products of bovine placental steroidogenesis
no association between the AR CAG polymorphism and the relative risk of prostate cancer in white Brazilian individuals with a CAG repeat (show CELF3 Antibodies)
FSHR (show FSHR Antibodies) is specifically regulated through androgen receptor in granulosa cells
Roles of IGF-I (show IGF1 Antibodies) and the estrogen, androgen and IGF-I (show IGF1 Antibodies) receptors in estradiol-17beta- and trenbolone acetate-stimulated proliferation of cultured bovine satellite cells.
In GD20 and PD2 (show PAF1 Antibodies) males we found the reduction of the luminal compartment, inflammatory changes, decreased androgen receptor and increased Cx43 (show GJA1 Antibodies) expression
Data suggest that signal transduction involving androgen receptor is involved in apoptosis of granulosa cells (as seen in follicular atresia).
Pig ejaculated spermatozoa express androgen receptor.
Androgen receptor (AR) and Wilms' tumor gene 1 expression dramatically decreased after heat treatment in Sertoli cells
Sertoli cell maturation during puberty in the stallion was accompanied by a reduced expression of anti-Mullerian hormone (show AMH Antibodies) and its receptor, arrest of cell proliferation, increased expression of androgen receptor
The vesicular gland of castrated goats showed significantly lower AR and COX-2 (show COX2 Antibodies) immuno-expression than intact goats indicating that both AR and COX-2 (show COX2 Antibodies) are androgen dependent.
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described.
androgen nuclear receptor variant 2
, dihydrotestosterone receptor
, nuclear receptor subfamily 3 group C member 4
, testicular feminization
, androgen receptor (Testicular feminization), same as Tfm
, androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)
, androgen receptor AR
, Ar beta
, androgen receptor
, prostate androgen receptor