anti-Mouse (Murine) Nuclear Receptor Subfamily 1, Group H, Member 3 antibody for Enzyme Immunoassay

Recommended Nuclear Receptor Subfamily 1, Group H, Member 3 Antibody

Antigen
Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) Antibodies
  • NR1H3
  • LXR-a
  • LXRA
  • RLD-1
  • AU018371
  • LXR
  • RLD1
  • Unr1
  • LXRalpha
  • LXR-alpha
  • im:7141239
  • wu:fd59b01
  • zgc:113339
  • zgc:158542
  • nuclear receptor subfamily 1 group H member 3
  • nuclear receptor subfamily 1, group H, member 3
  • NR1H3
  • nr1h3
  • Nr1h3
Epitope
N-Term
15
12
10
9
8
8
7
4
3
3
3
3
3
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
133
70
65
11
9
9
7
6
6
5
4
4
3
2
2
2
2
2
2
Host
Rabbit
122
15
6
Clonality
Polyclonal
Conjugate
Un-conjugated
7
5
5
2
2
2
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
119
58
26
15
9
8
7
6
4
2
2
2
1
1
Options

Available images

Catalog No. ABIN615720
$ 495.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
1 ABIN5554977 EIA IHC (p) WB Rabbit IgG N-Term Polyclonal 0

General

Antigen Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) Antibodies
Epitope N-Term
(15), (12), (10), (9), (8), (8), (7), (4), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(133), (70), (65), (11), (9), (9), (7), (6), (6), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2)
Host Rabbit
(122), (15), (6)
Clonality
Polyclonal
Conjugate Un-conjugated
(7), (5), (5), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(119), (58), (26), (15), (9), (8), (7), (6), (4), (2), (2), (2), (1), (1)
Supplier

Product details

Target Details Application Details Handling Images
Specificity This antibody reacts to the N-term of Liver X Receptor Alpha (LXR Alpha/NR1H3).
Purification Immunoaffinity Chromatography
Immunogen NR1H3 antibody was raised against synthetic peptide - KLH conjugated Genename: NR1H3

Target Details

Product details Application Details Handling Images back to top
Antigen
Alternative Name NR1H3 (NR1H3 Antibody Abstract)
Background Liver X receptor alpha (LXR alpha), a NR1 Thyroid Hormone-Like Receptor, has been shown to affect the transport and catabolism of cholesterol as well as fatty acid metabolism. LXR alpha also appears to be an important insulin mediating factor in the regulation of lipogenesis. LXR alpha is known to be activated by oxysterols and to regulate a wide range of genes, including members of the ATP-binding cassette (ABC) superfamily of transporter proteins (ABCA1 and ABCG1), surface constituents of plasma lipoproteins like apolipoprotein E, and cholesterol ester transport protein. The induced expression of LXR alpha may be related to foam-cell formation in atherosclerotic lesions. As a result, LXR alpha has been suggested as a potential therapeutic target for treating atherosclerosis. LXR alpha forms a heterodimer with RXR alpha and binds the DR4-type cis-element. Recently LXR alpha has been shown to act as a cAMP-responsive nuclear modulator of renin and c-myc expression, suggesting a possible involvement of LXR alpha in the cardiovascular system and in general gene transcription.Synonyms: LXRA, Liver X receptor alpha, Nuclear orphan receptor LXR-alpha, Nuclear receptor subfamily 1 group H member 3, Oxysterols receptor LXR-alpha
Gene ID 10062
NCBI Accession NP_001123573
UniProt Q13133
Pathways Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C

Application Details

Product details Target Details Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product details Target Details Application Details Images back to top
Concentration 1,0 mg/mL
Buffer PBS containing 0.02 % sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

Images

Product details Target Details Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (N-Term) antibody (ABIN615720) Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western Blotting (WB) image for anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (N-Term) antibody (ABIN615720) Western blot analysis of LXR-A in rat liver tissue lysate with LXR-A antibody at (A) ...