anti-Human Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) antibody for Immunocytochemistry

Recommended Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) Antibody

Antigen
Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) Antibodies
  • GR
  • gcr
  • grl
  • xGR
  • gccr
  • gr
  • zgc:113038
  • NR3C1
  • GCL
  • LOC100302444
  • Gcr
  • Grl
  • Grl-1
  • Grl1
  • GRL
  • GCCR
  • GCR
  • NO
  • GR-A
  • nr3c1
  • nuclear receptor subfamily 3 group C member 1
  • nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
  • nuclear receptor subfamily 3, group C, member 1
  • glucocorticoid receptor
  • NR3C1
  • nr3c1
  • LOC100302444
  • Nr3c1
Reactivity
Human
290
151
135
8
7
6
5
5
4
4
3
1
1
1
Host
Mouse
250
56
5
Clonality
Monoclonal
Conjugate
Un-conjugated
23
17
10
7
6
6
6
6
6
6
6
6
3
3
3
3
3
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
225
119
104
63
53
39
34
29
26
17
4
3
2
1
1
Options

Available images

Catalog No. ABIN969321
$ 430.10
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
28.448063 ABIN2854939 ICC IF IP IHC (p) WB Rabbit IgG N-Term Polyclonal 0
25.448063 ABIN2854940 ICC IF IHC (p) WB Rabbit IgG Center Polyclonal 0
13.926594 ABIN268501 BP ChIP FACS GS ICC IF IHC IHC (p) IP Neut WB Mouse IgG2 BuGR2 8
13 ABIN1860047 ICC IHC WB Rabbit IgG AA 532-730 Polyclonal 0
13 ABIN1174819 ICC IHC WB Rabbit IgG AA 41-184 Polyclonal 0
13 ABIN5774077 ELISA FACS ICC IF IHC (p) WB Mouse IgG1 6E6 0
10 ABIN6263722 ELISA ICC IF IHC WB Rabbit IgG Polyclonal 0
9.426594 ABIN152786 ChIP ICC IF IHC (p) IP IHC WB Rabbit IgG Polyclonal 1
9.426594 ABIN152763 ChIP ICC IF IHC (p) IHC WB Rabbit IgG Polyclonal 1
7 ABIN1859061 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 598-755 Polyclonal 0
1.9265938 ABIN4315970 ICC IF IHC IHC (p) IP WB Rabbit IgG Center Polyclonal 0
1.9265938 ABIN4315954 ELISA FACS ICC IF IHC IHC (p) WB Mouse IgG1 6E6 0
1.9265938 ABIN4315953 ICC IF IHC IHC (p) WB Rabbit IgG Polyclonal 0
1 ABIN6933577 ELISA ICC IF WB Rabbit IgG pSer203 Polyclonal 0
1 ABIN228188 ICC IF IP ELISA WB Rabbit IgG pSer211 Polyclonal 0
1 ABIN1918436 ELISA ICC IF IHC WB APC Rabbit IgG AA 236-262 Polyclonal 0
1 ABIN1918435 ELISA ICC IF IHC WB Alkaline Phosphatase (AP) Rabbit IgG AA 236-262 Polyclonal 0
1 ABIN1918437 ELISA ICC IF IHC WB Biotin Rabbit IgG AA 236-262 Polyclonal 0
1 ABIN1918438 ELISA ICC IF IHC WB FITC Rabbit IgG AA 236-262 Polyclonal 0
1 ABIN1918439 ELISA ICC IF IHC WB PE Rabbit IgG AA 236-262 Polyclonal 0

General

Antigen Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) Antibodies
Reactivity Human
(290), (151), (135), (8), (7), (6), (5), (5), (4), (4), (3), (1), (1), (1)
Host Mouse
(250), (56), (5)
Clonality (Clone)
Monoclonal   ( )
Conjugate Un-conjugated
(23), (17), (10), (7), (6), (6), (6), (6), (6), (6), (6), (6), (3), (3), (3), (3), (3), (1), (1)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(225), (119), (104), (63), (53), (39), (34), (29), (26), (17), (4), (3), (2), (1), (1)
Pubmed 2 references available
Supplier

Product details

Target Details Application Details Handling References Images
Purification Ascites
Immunogen Purified recombinant fragment of human NR3C1 expressed in E. Coli.
Clone 6-00E-06
Isotype IgG1

Target Details

Product details Application Details Handling References Images back to top
Antigen
Alternative Name NR3C1 (NR3C1 Antibody Abstract)
Background The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Tissue specificity: Widely expressed. In the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart.
Molecular Weight 86 kDa
Gene ID 2908
HGNC 2908
Pathways Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Regulation of Carbohydrate Metabolic Process

Application Details

Product details Target Details Handling References Images back to top
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only

Handling

Product details Target Details Application Details References Images back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

References

Product details Target Details Application Details Handling Images back to top
Product cited in:

Charmandari, Ichijo, Jubiz, Baid, Zachman, Chrousos, Kino: "A novel point mutation in the amino terminal domain of the human glucocorticoid receptor (hGR) gene enhancing hGR-mediated gene expression." in: The Journal of clinical endocrinology and metabolism, Vol. 93, Issue 12, pp. 4963-8, 2008

Oberlander, Weinberg, Papsdorf, Grunau, Misri, Devlin: "Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses." in: Epigenetics, Vol. 3, Issue 2, pp. 97-106, 2008

Images

Product details Target Details Application Details Handling References back to top
Supplier Images
ELISA image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) antibody (ABIN969321) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) antibody (ABIN969321) Figure 2: Flow cytometric analysis of K562 cells using NR3C1 mouse mAb (green) and ne...
Immunocytochemistry (ICC) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) antibody (ABIN969321) Figure 3: Immunofluorescence analysis of PC-2 cells using NR3C1 mouse mAb (green) . B...
Immunohistochemistry (IHC) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) antibody (ABIN969321) Figure 4: Immunohistochemical analysis of paraffin-embedded lung cancer tissues using...
Western Blotting (WB) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) antibody (ABIN969321) Figure 5: Western blot analysis using NR3C1 mouse mAb against Hela cell lysate.