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PARG Products

(PARG)

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Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. [provided by RefSeq, Jul 2008].

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Featured PARG Categories

PARG Antibodies

High quality antibodies with extensive validation data.

PARG ELISA Kits

Reliable ELISA kits for a wide range of species.

PARG Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PARG Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
  • (3)
Cat. No. ABIN521952
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN391439
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7163765
Quantity 100 μg
Datasheet Datasheet

Recommended PARG ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1148562
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1148563
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1148564
Quantity 96 tests
Datasheet Datasheet

Recommended PARG Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314006
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314005
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
Cat. No. ABIN2745792
Quantity 2 μg
Datasheet Datasheet

Latest Publications for our PARG products

Marques, Jangal, Wang, Kazanets, da Silva, Zhao, Lovato, Yu, Jie, Del Rincon, Mackey, Damaraju, Alaoui-Jamali, Witcher: "Oncogenic activity of poly (ADP-ribose) glycohydrolase." in: Oncogene, Vol. 38, Issue 12, pp. 2177-2191, (2019) (PubMed).

Boudra, Bolin, Chiker, Fouquin, Zaremba, Vaslin, Biard, Cordelières, Mégnin-Chanet, Favaudon, Fernet, Pennaneach, Hall: "PARP-2 depletion results in lower radiation cell survival but cell line-specific differences in poly(ADP-ribose) levels." in: Cellular and molecular life sciences : CMLS, Vol. 72, Issue 8, pp. 1585-97, (2015) (PubMed).

Arena, Mistretta, Di Natale, Mennella, De Santo, De Maio: "Characterization and role of poly(ADP-ribosyl)ation in the Mediterranean species Cistus incanus L. under different temperature conditions." in: Plant physiology and biochemistry : PPB / Société française de physiologie végétale, Vol. 49, Issue 4, pp. 435-40, (2011) (PubMed).

Majewski, Thurston, Ramalingam, Kiela, Ghishan: "Cooperative role of NF-{kappa}B and poly(ADP-ribose) polymerase 1 (PARP-1) in the TNF-induced inhibition of PHEX expression in osteoblasts." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34828-38, (2010) (PubMed).

Meyer, Meyer-Ficca, Whatcott, Jacobson, Jacobson: "Two small enzyme isoforms mediate mammalian mitochondrial poly(ADP-ribose) glycohydrolase (PARG) activity." in: Experimental cell research, Vol. 313, Issue 13, pp. 2920-36, (2007) (PubMed).

Fisher, Hochegger, Takeda, Caldecott: "Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase." in: Molecular and cellular biology, Vol. 27, Issue 15, pp. 5597-605, (2007) (PubMed).

Keil, Gröbe, Oei: "MNNG-induced cell death is controlled by interactions between PARP-1, poly(ADP-ribose) glycohydrolase, and XRCC1." in: The Journal of biological chemistry, Vol. 281, Issue 45, pp. 34394-405, (2006) (PubMed).

Synonyms and alternative names related to PARG

poly(ADP-ribose) glycohydrolase (PARG), poly (ADP-ribose) glycohydrolase (Parg), AI413217, PARG99

Protein level used designations for PARG

  • mitochondrial poly(ADP-ribose) glycohydrolase
  • poly(ADP-ribose) glycohydrolase
  • poly(ADP-ribose) glycohydrolase 60 kDa isoform
  • cytosolic poly(ADP-ribose) glycohydrolase
  • mitochondrial poly(ADP-ribose) glycohydrolase 63 kDa isoform
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