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P2RY1 Products

(Purinergic Receptor P2Y, G-Protein Coupled, 1 (P2RY1))

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The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008].

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Featured P2RY1 Categories

P2RY1 Antibodies

High quality antibodies with extensive validation data.

P2RY1 ELISA Kits

Reliable ELISA kits for a wide range of species.

P2RY1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended P2RY1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application ELISA, WB, IHC, FACS, ICC, Neut
Validations
  • (8)
Cat. No. ABIN5611276
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Guinea Pig, Hamster, Human, Monkey, Mouse, Rabbit, Rat
Application IHC, IHC (p), ICC
Validations
  • (5)
Cat. No. ABIN1049199
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IF
Validations
  • (1)
  • (3)
Cat. No. ABIN518571
Quantity 50 μg
Datasheet Datasheet

Recommended P2RY1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971297
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958995
Quantity 96 tests
Datasheet Datasheet

Recommended P2RY1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313817
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3098273
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7408402
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our P2RY1 products

Meacham, Cortés, Wiggins, Maass, Latorre, Ralle, Burkhead: "Altered zinc balance in the Atp7b-/- mouse reveals a mechanism of copper toxicity in Wilson disease." in: Metallomics : integrated biometal science, Vol. 10, Issue 11, pp. 1595-1606, (2018) (PubMed).

Coyle, ODonnell, Puri: "Altered distribution of small-conductance calcium-activated potassium channel SK3 in Hirschsprung's disease." in: Journal of pediatric surgery, Vol. 50, Issue 10, pp. 1659-64, (2015) (PubMed).

Heine, Sygnecka, Scherf, Grohmann, Bräsigk, Franke: "P2Y(1) receptor mediated neuronal fibre outgrowth in organotypic brain slice co-cultures." in: Neuropharmacology, Vol. 93, pp. 252-66, (2015) (PubMed).

Dilip, Ishii, Imada, Wada-Kiyama, Kiyama, Miyachi, Kaneda: "Distribution and development of P2Y1-purinoceptors in the mouse retina." in: Journal of molecular histology, Vol. 44, Issue 6, pp. 639-44, (2013) (PubMed).

Guns, Van Assche, Fransen, Robaye, Boeynaems, Bult: "Endothelium-dependent relaxation evoked by ATP and UTP in the aorta of P2Y2-deficient mice." in: British journal of pharmacology, Vol. 147, Issue 5, pp. 569-74, (2006) (PubMed).

Arthur, Shen, Mu, Leon, Gachet, Berndt, Andrews: "Calmodulin interacts with the platelet ADP receptor P2Y1." in: The Biochemical journal, Vol. 398, Issue 3, pp. 339-43, (2006) (PubMed).

Savi, Zachayus, Delesque-Touchard, Labouret, Hervé, Uzabiaga, Pereillo, Culouscou, Bono, Ferrara, Herbert: "The active metabolite of Clopidogrel disrupts P2Y12 receptor oligomers and partitions them out of lipid rafts." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 29, pp. 11069-74, (2006) (PubMed).

Ghanem, Robaye, Leal, Leipziger, Van Driessche, Beauwens, Boeynaems: "The role of epithelial P2Y2 and P2Y4 receptors in the regulation of intestinal chloride secretion." in: British journal of pharmacology, Vol. 146, Issue 3, pp. 364-9, (2005) (PubMed).

Flores, Hernández-Pérez, Aquino, Garrad, Weisman, Gonzalez: "Agonist-induced phosphorylation and desensitization of the P2Y2 nucleotide receptor." in: Molecular and cellular biochemistry, Vol. 280, Issue 1-2, pp. 35-45, (2005) (PubMed).

Synonyms and alternative names related to P2RY1

purinergic receptor P2Y, G-protein coupled 1 (P2ry1), purinergic receptor P2Y1 (P2ry1), purinergic receptor P2Y1 (P2RY1), P2y, P2Y1, P2y1

Protein level used designations for P2RY1

  • ATP receptor
  • P2Y purinoceptor 1
  • P2Y1 receptor
  • P2Y1 purinoceptor
  • P2 purinoceptor subtype Y1
  • platelet ADP receptor
  • P2 purinoreceptor subclass 2Y
  • P2Y ATP receptor 1
  • ATP receptor P2Y1
  • G protein-coupled receptor
  • P2Y1
  • p2y1 purinoceptor
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