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P4HA2 Products

(Prolyl 4-Hydroxylase, alpha Polypeptide II (P4HA2))
This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

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Featured P4HA2 Categories

P4HA2 Antibodies

High quality antibodies with extensive validation data.

P4HA2 ELISA Kits

Reliable ELISA kits for a wide range of species.

P4HA2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended P4HA2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ELISA
Validations
  • (4)
Cat. No. ABIN7164785
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN1681193
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7435769
Quantity 100 μL
Datasheet Datasheet

Recommended P4HA2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969622
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958834
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1150196
Quantity 96 tests
Datasheet Datasheet

Recommended P4HA2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313834
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3085330
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3122721
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our P4HA2 products

Gilkes, Bajpai, Chaturvedi, Wirtz, Semenza: "Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts." in: The Journal of biological chemistry, Vol. 288, Issue 15, pp. 10819-29, (2013) (PubMed).

Gilkes, Chaturvedi, Bajpai, Wong, Wei, Pitcairn, Hubbi, Wirtz, Semenza: "Collagen prolyl hydroxylases are essential for breast cancer metastasis." in: Cancer research, Vol. 73, Issue 11, pp. 3285-96, (2013) (PubMed).

Berger, Capper, Lemke, Pfenning, Platten, Weller, von Deimling, Wick, Weiler: "Defective p53 antiangiogenic signaling in glioblastoma." in: Neuro-oncology, Vol. 12, Issue 9, pp. 894-907, (2010) (PubMed).

Synonyms and alternative names related to P4HA2

prolyl 4-hydroxylase subunit alpha 2 (P4HA2), prolyl 4-hydroxylase, alpha polypeptide II (P4HA2), procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide (P4ha2), prolyl 4-hydroxylase subunit alpha 2 (P4ha2), AA407196, C76437, P4hl

Protein level used designations for P4HA2

  • prolyl 4-hydroxylase subunit alpha-2
  • procollagen-proline, 2-oxoglutarate 4-dioxygenase, alpha polypeptide II, isoform 1
  • prolyl 4-hydroxylase, alpha II subunit
  • prolyl 4-hydroxylase, alpha polypeptide II
  • prolyl 4-hydroxylase subunit alpha-2-like
  • 4-PH alpha-2
  • Prolyl 4-hydroxylase alpha IIa subunit
  • procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2
  • 4-PH alpha 2
  • C-P4Halpha(II)
  • collagen prolyl 4-hydroxylase alpha(II)
  • procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II
  • procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide
  • prolyl 4-hydroxylase alpha-2 subunit
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