anti-Mouse (Murine) CHEK2 antibody for Western Blotting

Recommended CHEK2 Antibody (supplied by: Log in to see )

Antigen
Checkpoint Kinase 2 (CHEK2) Antibodies
  • CDS1
  • CHK2
  • HuCds1
  • LFS2
  • PP1425
  • RAD53
  • hCds1
  • fa66f08
  • wu:fa66f08
  • zgc:55865
  • Cds1
  • HUCDS1
  • Rad53
  • Chk2
  • cds1
  • chek2
  • chk2
  • hucds1
  • lfs2
  • pp1425
  • rad53
  • checkpoint kinase 2
  • serine/threonine-protein kinase chk2
  • checkpoint kinase 2 L homeolog
  • CHEK2
  • chek2
  • Chek2
  • MCYG_07308
  • chek2.L
Reactivity
Mouse (Murine), Rat (Rattus), Human
503
227
203
25
18
16
13
8
5
4
3
1
1
1
1
1
Host
Rabbit
387
118
8
1
1
Clonality
Polyclonal
Conjugate
This CHEK2 antibody is un-conjugated
10
10
9
7
7
5
5
5
5
5
5
5
5
5
4
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
418
151
149
104
99
66
50
44
34
10
6
4
2
1
1
Options
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Available images

Catalog No. ABIN3023035
$ 393.25
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
23.063175 ABIN3181964 ELISA IHC WB Rabbit IgG pThr68 Log in to see Polyclonal 0
20.063175 ABIN3183907 ELISA IHC WB Rabbit IgG Tyr60 Log in to see Polyclonal 0
19.806385 ABIN6256554 ELISA ICC IF IHC WB Rabbit IgG pThr387 Log in to see Polyclonal 0
19.806385 ABIN6256592 ELISA ICC IF IHC WB Rabbit IgG pThr68 Log in to see Polyclonal 0
19.806385 ABIN6256552 ELISA ICC IF IHC WB Rabbit IgG pThr383 Log in to see Polyclonal 0
19.806385 ABIN6271230 ELISA ICC IF IHC WB Rabbit IgG pSer28, pThr26 Log in to see Polyclonal 0
19.806385 ABIN6255391 ELISA ICC IF IHC WB Rabbit IgG pSer516 Log in to see Polyclonal 0
19.806385 ABIN1871829 ICC IF IHC IP WB Rabbit IgG Log in to see Polyclonal 0
17.063175 ABIN3183906 ELISA IHC WB Rabbit IgG Tyr599 Log in to see Polyclonal 0
17.063175 ABIN3183904 ELISA IHC WB Rabbit IgG Tyr594 Log in to see Polyclonal 0
17.063175 ABIN3182426 ELISA IF WB Rabbit IgG pThr383 Log in to see Polyclonal 0
17.063175 ABIN3182510 ELISA IHC WB Rabbit IgG pThr387 Log in to see Polyclonal 0
16.806385 ABIN6566595 IF IHC IP WB Rabbit IgG Log in to see Polyclonal 0
13.806385 ABIN6260810 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0
13.25679 ABIN2137570 IHC ELISA WB Rabbit IgG pThr387 Log in to see Polyclonal 0
13.25679 ABIN2137572 IF ELISA WB Rabbit IgG pThr383 Log in to see Polyclonal 0
13.25679 ABIN1689968 WB Rabbit Log in to see Polyclonal 0
11.5 ABIN685867 IF (p) IHC (p) WB Rabbit IgG AA 120-160 Log in to see Polyclonal 2
11.5 ABIN703165 IF (p) IHC (p) WB Rabbit IgG AA 50-90, pThr68 Log in to see Polyclonal 2
10.806385 ABIN6260800 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen Checkpoint Kinase 2 (CHEK2) Antibodies
Reactivity Mouse (Murine), Rat (Rattus), Human
(503), (227), (203), (25), (18), (16), (13), (8), (5), (4), (3), (1), (1), (1), (1), (1)
Host Rabbit
(387), (118), (8), (1), (1)
Clonality
Polyclonal
Conjugate This CHEK2 antibody is un-conjugated
(10), (10), (9), (7), (7), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(418), (151), (149), (104), (99), (66), (50), (44), (34), (10), (6), (4), (2), (1), (1)
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Product Details anti-CHEK2 Antibody

Target Details CHEK2 Application Details Handling Images
Purification Affinity purification
Immunogen Recombinant protein of human CHEK2
Isotype IgG
Plasmids, Primers & others

Target Details CHEK2

Product Details anti-CHEK2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CHEK2 (CHEK2 Antibody Abstract)
Background Chk2 is the mammalian orthologue of the budding yeast Rad53 and fission yeast Cds1 checkpoint kinases. The amino-terminal domain of Chk2 contains a series of seven serine or threonine residues (Ser19, Thr26, Ser28, Ser33, Ser35, Ser50, and Thr68) each followed by glutamine (SQ or TQ motif). These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function. Phosphorylation at Thr68 is a prerequisite for the subsequent activation step, which is attributable to autophosphorylation of Chk2 at residues Thr383 and Thr387 in the activation loop of the kinase domain.
Synonyms: CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53
Gene ID 11200
UniProt O96017
Pathways p53 Signaling, Apoptosis, Cell Division Cycle

Application Details

Product Details anti-CHEK2 Antibody Target Details CHEK2 Handling Images back to top
Application Notes Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
Restrictions For Research Use only

Handling

Product Details anti-CHEK2 Antibody Target Details CHEK2 Application Details Images back to top
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze / thaw cycles
Storage -20 °C/-80 °C

Images

Product Details anti-CHEK2 Antibody Target Details CHEK2 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Checkpoint Kinase 2 (CHEK2) antibody (ABIN3023035) anti-Checkpoint Kinase 2 (CHEK2) antibody
Western Blotting (WB) image for anti-Checkpoint Kinase 2 (CHEK2) antibody (ABIN3023035) Western blot analysis of extracts of various cell lines, using CHEK2 antibody.
Western Blotting (WB) image for anti-Checkpoint Kinase 2 (CHEK2) antibody (ABIN3023035) Western blot analysis of extracts of various cell lines, using CHEK2 antibody.
Immunofluorescence (IF) image for anti-Checkpoint Kinase 2 (CHEK2) antibody (ABIN3023035) Immunofluorescence analysis of MCF-7 cells using CHEK2 antibody.
Immunofluorescence (IF) image for anti-Checkpoint Kinase 2 (CHEK2) antibody (ABIN3023035) Immunofluorescence analysis of A549 cells using CHEK2 antibody.