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PAI1 Proteins

(Plasminogen Activator Inhibitor 1 (SERPINE1))
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].

Active filters:

  • Target: PAI1 (SERPINE1)
  • Protein
Catalog no. Product Reactivity Host / Clonality Application Price & lead time
ABIN1319636
PAI1 Protein (AA 1-402) (GST tag) SERPINE1 · Protein Human Wheat germ
  • AP (Affinity Purification: Listed application)
  • AA (Antibody Array: Listed application)
  • ELISA (ELISA: Listed application)
  • WB (Western Blotting: Listed application)
$475.39 View price
  • 10 μg
  • 25 μg
Delivery in 11 to 14 Business Days Shipping to: United States
ABIN7124465
PAI1 Protein (AA 24-402) (His tag) SERPINE1 · Protein Human Escherichia coli (E. coli)
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
$510.30 View price
  • 50 μg
  • 1 mg
  • 200 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN7124467
PAI1 Protein (AA 24-402) (His tag) SERPINE1 · Protein Pig Escherichia coli (E. coli)
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
$569.57 View price
  • 50 μg
  • 1 mg
  • 200 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN7852330
PAI1 Protein (AA 24-402) (His tag) SERPINE1 · Protein Human Mammalian Cells
  • SDS (SDS-PAGE: Validation image available)
$496.97 View price
  • 100 μg
  • 10 μg
  • 50 μg
Delivery in 12 to 15 Business Days Shipping to: United States
ABIN7320628
PAI1 Protein (AA 22-402) (His tag) SERPINE1 · Protein Mouse HEK-293 Cells
  • WB (Western Blotting: Validation image available)
$513.17 View price
  • 50 μg
  • 10 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN1319638
PAI1 Protein (AA 86-185) (GST tag) SERPINE1 · Protein Human Wheat germ
  • AP (Affinity Purification: Listed application)
  • AA (Antibody Array: Listed application)
  • ELISA (ELISA: Listed application)
  • WB (Western Blotting: Listed application)
$475.39 View price
  • 10 μg
  • 25 μg
Delivery in 11 to 14 Business Days Shipping to: United States
ABIN1048113
PAI1 Protein SERPINE1 · Protein Human –
$1,339.33 View price
  • 50 μg
  • 10 μg
Delivery in 5 to 8 Business Days Shipping to: United States
ABIN7889842
PAI1 Protein (AA 24-402) (Fc Tag) SERPINE1 · Protein Human Human Cells
$2,761.55 View price
  • 1 mg
Delivery in 4 to 5 Business Days Shipping to: United States
ABIN573685
PAI1 Protein SERPINE1 · Protein Mouse Escherichia coli (E. coli)
$2,647.26 View price
  • 500 μg
Delivery in 2 to 4 Business Days Shipping to: United States
ABIN7504500
PAI1 Protein (AA 24-402) (His tag) SERPINE1 · Protein Rat HEK-293 Cells
$349.67 View price
  • 100 μg
  • 500 μg
Delivery in 3 to 6 Business Days Shipping to: United States
ABIN7866048
PAI1 Protein (AA 24-402) SERPINE1 · Protein Human Escherichia coli (E. coli)
$128.19 View price
  • 2 μg
Delivery in 9 to 12 Business Days Shipping to: United States
ABIN7664967
PAI1 Protein (AA 349-390) (His-IF2DI Tag) SERPINE1 · Protein Human Escherichia coli (E. coli)
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
$510.30 View price
  • 50 μg
  • 1 mg
  • 200 μg
Delivery in 15 to 20 Business Days Shipping to: United States
ABIN7664966
PAI1 Protein (AA 22-402) (His tag) SERPINE1 · Protein Monkey Escherichia coli (E. coli)
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
$658.46 View price
  • 50 μg
  • 1 mg
  • 200 μg
Delivery in 15 to 20 Business Days Shipping to: United States
ABIN7664968
PAI1 Protein (AA 24-402) (His tag) SERPINE1 · Protein Cow Escherichia coli (E. coli)
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
$569.57 View price
  • 50 μg
  • 1 mg
  • 200 μg
Delivery in 15 to 20 Business Days Shipping to: United States
ABIN1691566
PAI1 Protein (AA 24-402) (His tag) SERPINE1 · Protein Mouse Human Cells
$627.11 View price
  • 50 μg
  • 1 mg
  • 10 μg
  • 500 μg
Delivery in 4 to 5 Business Days Shipping to: United States
ABIN935739
PAI1 Protein SERPINE1 · Protein Human Escherichia coli (E. coli)
$784.75 View price
  • 10 μg
Delivery in 16 to 22 Business Days Shipping to: United States
ABIN7669431
PAI1 Protein (AA 24-402) (His tag) SERPINE1 · Protein Human HEK-293 Cells
  • Imm (Immunogen: Listed application)
$1,902.46 View price
  • 500 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN7704276
PAI1 Protein (AA 22-402) (His tag) SERPINE1 · Protein Mouse Mammalian Cells
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
$658.46 View price
  • 50 μg
  • 1 mg
  • 10 μg
  • 500 μg
Delivery in 15 to 20 Business Days Shipping to: United States
ABIN7197367
PAI1 Protein (His tag) SERPINE1 · Protein Human HEK-293 Cells
$926.62 View price
  • 50 μg
  • 1 mg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN7669430
PAI1 Protein (AA 1-402) (His tag) SERPINE1 · Protein Rat Mammalian Cells
  • Imm (Immunogen: Listed application)
$1,902.46 View price
  • 500 μg
Delivery in 11 to 15 Business Days Shipping to: United States
Protein
  • AP (Affinity Purification: Listed application)
  • AA (Antibody Array: Listed application)
  • ELISA (ELISA: Listed application)
  • WB (Western Blotting: Listed application)
Origin
Human
Host
Wheat germ
Protein Type
Recombinant
Catalog No. ABIN1319636
$475.39
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
Protein
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
Greater than 90 % as determined by SDS-PAGE.
Catalog No. ABIN7124465
$510.30
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • WB (Western Blotting: Validation image available)
  • ELISA (ELISA: Listed application)
Origin
Pig
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
Greater than 90 % as determined by SDS-PAGE.
Catalog No. ABIN7124467
$569.57
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
Origin
Human
Host
Mammalian Cells
Protein Type
Recombinant
Purity
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7852330
$496.97
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 12 to 15 Business Days
Protein
  • WB (Western Blotting: Validation image available)
Origin
Mouse
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7320628
$513.17
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • AP (Affinity Purification: Listed application)
  • AA (Antibody Array: Listed application)
  • ELISA (ELISA: Listed application)
  • WB (Western Blotting: Listed application)
Origin
Human
Host
Wheat germ
Protein Type
Recombinant
Catalog No. ABIN1319638
$475.39
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
Protein
Origin
Human
Protein Type
Recombinant
Purity
> 95 % (SDS-PAGE)
Catalog No. ABIN1048113
$1,339.33
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 5 to 8 Business Days
Protein
Origin
Human
Host
Human Cells
Protein Type
Recombinant
Catalog No. ABIN7889842
$2,761.55
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 4 to 5 Business Days
Protein
Origin
Mouse
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 98 % pure (SDS-PAGE)
Catalog No. ABIN573685
$2,647.26
Plus shipping costs $50.00, if applicable $20.00 dry ice
500 μg
Shipping to: United States
Delivery in 2 to 4 Business Days
Protein
Origin
Rat
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
Biological Activity
Active
Catalog No. ABIN7504500
$349.67
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 3 to 6 Business Days
Protein
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
>95 % , as determined by SDS-PAGE and HPLC
Biological Activity
Active
Catalog No. ABIN7866048
$128.19
Plus shipping costs $50.00
2 μg
Shipping to: United States
Delivery in 9 to 12 Business Days
Protein
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
Greater than 90 % as determined by SDS-PAGE.
Catalog No. ABIN7664967
$510.30
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 20 Business Days
Protein
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
Origin
Monkey
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
Greater than 90 % as determined by SDS-PAGE.
Catalog No. ABIN7664966
$658.46
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 20 Business Days
Protein
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
Origin
Cow
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
Greater than 90 % as determined by SDS-PAGE.
Catalog No. ABIN7664968
$569.57
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 20 Business Days
Protein
Origin
Mouse
Host
Human Cells
Protein Type
Recombinant
Purity
> 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1691566
$627.11
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 4 to 5 Business Days
Protein
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 98 % pure
Biological Activity
Active
Catalog No. ABIN935739
$784.75
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 16 to 22 Business Days
Protein
  • Imm (Immunogen: Listed application)
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7669431
$1,902.46
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • WB (Western Blotting: Listed application)
  • ELISA (ELISA: Listed application)
Origin
Mouse
Host
Mammalian Cells
Protein Type
Recombinant
Purity
Greater than 95 % as determined by SDS-PAGE.
Catalog No. ABIN7704276
$658.46
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 20 Business Days
Protein
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 97 % as determined by reducing SDS-PAGE.
Biological Activity
Active
Catalog No. ABIN7197367
$926.62
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • Imm (Immunogen: Listed application)
Origin
Rat
Host
Mammalian Cells
Protein Type
Recombinant
Purity
> 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7669430
$1,902.46
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 15 Business Days

Latest Publications for our PAI1 Proteins

Reichel, Hessenauer, Pflieger, Rehberg, Kanse, Zahler, Krombach, Berghaus, Strieth: "Components of the Plasminogen Activation System Promote Engraftment of Porous Polyethylene Biomaterial via Common and Distinct Effects." in: PLoS ONE, Vol. 10, Issue 2, pp. e0116883, (2015) (PubMed).

Florova, Azghani, Karandashova, Schaefer, Koenig, Stewart-Evans, Declerck, Idell, Komissarov: "Targeting of plasminogen activator inhibitor 1 improves fibrinolytic therapy for tetracycline-induced pleural injury in rabbits." in: American journal of respiratory cell and molecular biology, Vol. 52, Issue 4, pp. 429-37, (2015) (PubMed).

Dinarvand, Hassanian, Weiler, Rezaie: "Intraperitoneal administration of activated protein C prevents postsurgical adhesion band formation." in: Blood, Vol. 125, Issue 8, pp. 1339-48, (2015) (PubMed).

Simone, Higgins, Archambeault, Higgins, Ginnan, Singer, Higgins: "A small molecule PAI-1 functional inhibitor attenuates neointimal hyperplasia and vascular smooth muscle cell survival by promoting PAI-1 cleavage." in: Cellular signalling, Vol. 27, Issue 5, pp. 923-33, (2015) (PubMed).

Yang, Kuan: "Anti-tissue plasminogen activator (tPA) as an effective therapy of neonatal hypoxia-ischemia with and without inflammation." in: CNS neuroscience & therapeutics, Vol. 21, Issue 4, pp. 367-73, (2015) (PubMed).

Komissarov, Florova, Azghani, Buchanan, Bradley, Schaefer, Koenig, Idell: "The time course of resolution of adhesions during fibrinolyitic therapy in tetracycline-induced pleural injury in rabbits." in: American journal of physiology. Lung cellular and molecular physiology, pp. ajplung.00136.2015, (2015) (PubMed).

Damare, Brandal, Fortenberry: "Inhibition of PAI-1 antiproteolytic activity against tPA by RNA aptamers." in: Nucleic acid therapeutics, Vol. 24, Issue 4, pp. 239-49, (2014) (PubMed).

Wan, Gao, Zhou, Zhang, Hao, Lian, Li, Chen, Liu: "SIRT1-mediated epigenetic downregulation of plasminogen activator inhibitor-1 prevents vascular endothelial replicative senescence." in: Aging cell, Vol. 13, Issue 5, pp. 890-9, (2014) (PubMed).

Florova, Karandashova, Declerck, Idell, Komissarov: "Remarkable stabilization of plasminogen activator inhibitor 1 in a "molecular sandwich" complex." in: Biochemistry, Vol. 52, Issue 27, pp. 4697-709, (2013) (PubMed).

Komissarov, Florova, Azghani, Karandashova, Kurdowska, Idell: "Active ?-macroglobulin is a reservoir for urokinase after fibrinolytic therapy in rabbits with tetracycline-induced pleural injury and in human pleural fluids." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 305, Issue 10, pp. L682-92, (2013) (PubMed).

Aliases for PAI1 Proteins

serpin family E member 1 (SERPINE1) Proteins
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog (serpine1.L) Proteins
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (serpine1) Proteins
serine (or cysteine) peptidase inhibitor, clade E, member 1 (Serpine1) Proteins
serpin family E member 1 (Serpine1) Proteins
PAI Proteins
PAI-1 Proteins
PAI1 Proteins
Pai1 Proteins
PAI1A Proteins
Pai1aa Proteins
Planh Proteins
PLANH1 Proteins
Planh1 Proteins
RATPAI1A Proteins
SERPINE1 Proteins
si:ch211-138a11.1 Proteins
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