PDL2 Detection Set (Risk Free)
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- Target See all PDCD1LG2 products
- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
- Binding Specificity
- Extracellular Domain
- Reactivity
- Human
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Host
- Mouse
- Clonality
- Monoclonal
- Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Brand
- Risk-Free™
- Characteristics
- Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PD-L2 can act to stimulate an immunogenic response through an alternative receptor from PD-1.
- Purification
- Antibodies are supplied as protein A purified IgG1.
- Components
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PD-L2 Antibody [4E10]
PD-L2 Antibody [8C12]
PD-L2 Antibody [7C7]
PD-L2 Antibody [7C1]
PD-L2 Antibody [10H4] - Immunogen
- Mouse monoclonal PD-L2 antibodies were raised against the extracellular domain of human PD-L2.
- Isotype
- IgG1
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PDCD1LG2 (Human) Matched Antibody Pair
ELISA Reactivity: Human ELISA unconjugated Host: Mouse
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- Comment
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Risk-Free™ antibodies are monoclonal antibodies made to improve in vitro studies.
Unlike antibodies developed using proteins made in yeast or bacteria, Risk-Free™ antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein.
These antibodies have the following advantages:
- Antibodies are developed against mammalian-expressed, post-translationally modified recombinant proteins.
- Multiple antibodies per target allows the user to choose the best antibody for their application
- Available individually or as a set
- Risk-Free™ means they are rigorously tested and guaranteed to work for their designated applications:
- ELISA
- Flow Cytometry
- Immunoblot
- Immunohistochemistry
- Immunocytochemistry
- Immunofluorescence - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
- Alternative Name
- PDL2 (PDCD1LG2 Products)
- Synonyms
- PDL2 Matched Antibody Pair, B7DC Matched Antibody Pair, Btdc Matched Antibody Pair, CD273 Matched Antibody Pair, PD-L2 Matched Antibody Pair, PDCD1L2 Matched Antibody Pair, bA574F11.2 Matched Antibody Pair, B7-DC Matched Antibody Pair, F730015O22Rik Matched Antibody Pair, programmed cell death 1 ligand 2 Matched Antibody Pair, PDCD1LG2 Matched Antibody Pair, Pdcd1lg2 Matched Antibody Pair
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