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PD-L1 Proteins

(CD274 (PD-L1))
Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

80 results

PD-L1 Origin: Mouse Host: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. WB, SDS, ELISA, Imm, AcA Active
Catalog No. ABIN7607706
 
PD-L1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Catalog No. ABIN1348592
 
PD-L1 Origin: Mouse Host: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
Catalog No. ABIN7194779
 
PD-L1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90% by SDS-PAGE SDS
Catalog No. ABIN6386958
 
PD-L1 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95% by SDS-PAGE SDS, AcA Active
Catalog No. ABIN7281265
 
PD-L1 Origin: Mouse Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN2181635
 
PD-L1 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN7013168
 
PD-L1 Origin: Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN2181633
 
PD-L1 Origin: Mouse Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN2870578
 
PD-L1 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN6810006
 
PD-L1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7597264
 
PD-L1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7597263
 
PD-L1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505141
 
PD-L1 Origin: Dog Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7597224
 
PD-L1 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318878
 
PD-L1 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318879
 
PD-L1 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN4371365
 
PD-L1 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1096071
 
PD-L1 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN4371362
 
PD-L1 Origin: Rat Host: Mammalian Cells Recombinant Greater than 95 % as determined by SDS-PAGE. WB, ELISA
Catalog No. ABIN7663068
 
  • Type Protein
    • Protein
  • Application
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Production (AbP)
    • Standard (STD)
    • Antibody Array (AA)
    • Functional Studies (Func)
    • Mass Spectrometry (MS)
    • Protein Interaction (PI)
  • Reactivity
    • Human
    • Mouse
    • Cynomolgus
    • Rhesus Monkey
    • Dog
    • Rat
    • Rabbit
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • HEK-293 Cells
    • Human Cells
    • Escherichia coli (E. coli)
    • Mammalian Cells
    • CHO Cells
    • Wheat germ
    • Baculovirus infected Insect Cells
    • HEK-293T Cells
    • Insect cells (Sf9)
  • Binding Specificity
    • AA 19-238
    • AA 19-239
    • AA 1-239
    • AA 18-238
    • AA 19-134
    • AA 19-237
    • AA 34-241
    • partial
    • AA 1-238
    • AA 128-238
    • AA 141-240
    • AA 19-132
    • AA 19-226
    • AA 24-234
    • AA 48-290
  • Conjugate
    • His tag
    • Fc Tag
    • Un-conjugated
    • DYKDDDDK Tag
    • mFc Tag
    • Fc Tag,AVI tag
    • Fc Tag,AVI tag,Biotin
    • Fc Tag,His tag
    • His tag,AVI tag,Biotin
    • His tag,Biotin
    • His-Avi Tag,Biotin
    • DYKDDDDK-His Tag
    • Fc Tag,ECD
    • GST tag
    • His tag,Fc Tag,AVI tag,Biotin
    • His tag,GST tag
    • His-DYKDDDDK-Strep II Tag
    • His-IF2DI Tag
    • Llama Fc Tag
    • SUMO Tag
    • Strep Tag
    • Twin-Strep tag
    • hIgG-His-tag
    • mFc-His Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
    • Frozen
  • Biological Activity
    • Biologically Active
    • Biologically Inactive
  • Grade
    • MALS verified
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • ProSci
    • OriGene
    • Cohesion Biosciences
    • ProteoGenix

Latest Publications for our PD-L1 Proteins

Ye, Yuan, Yue, Rubin, Chen: "Focused Ultrasound-Enhanced Delivery of Intranasally Administered Anti-Programmed Cell Death-Ligand 1 Antibody to an Intracranial Murine Glioma Model." in: Pharmaceutics, Vol. 13, Issue 2, (2021) (PubMed).

Li, Ren, Zhao, Lou: "PD-L1 aptamer isolation via Modular-SELEX and its applications in cancer cell detection and tumor tissue section imaging." in: The Analyst, Vol. 146, Issue 9, pp. 2910-2918, (2021) (PubMed).

Fan, Tian, Chen, Liu, Zhou, He, Coleman, Dong, Li, Huang, Xu, Zhang, Gao, Zhou, Ding, Chen: "Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors." in: EMBO molecular medicine, Vol. 12, Issue 6, pp. e11571, (2020) (PubMed).

Li, Course, McNeish, Drescher, Valdmanis, Lieber: "Prophylactic In Vivo Hematopoietic Stem Cell Gene Therapy with an Immune Checkpoint Inhibitor Reverses Tumor Growth in Syngeneic Mouse Tumor Models." in: Cancer research, Vol. 80, Issue 3, pp. 549-560, (2020) (PubMed).

Lu, Xue, Deng, Zhou, Yu, Deng, Huang, Yi, Liang, Wang, Shen, Tong, Wang, Li, Song, Li, Su, Ding, Gong, Zhu, Wang, Zou, Zhang, Li, Zhou, Liu, Yu, Wang, Zhang, Yin, Xia, Zeng, Zhou, Ying, Chen, Wei, Li et al.: "Safety and feasibility of CRISPR-edited T cells in patients with refractory non-small-cell lung cancer. ..." in: Nature medicine, Vol. 26, Issue 5, pp. 732-740, (2020) (PubMed).

Wang, Ni, Zhou, He, Gao, Wu, Wu, Wu, Qiu, Zhou, Chen, Pan, Huang, Li, Bian, Yang, Miao, Liu: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." in: Cancer immunology, immunotherapy : CII, (2020) (PubMed).

Tocheva, Lerrer, Mor: "In Vitro Assays to Study PD-1 Biology in Human T Cells." in: Current protocols in immunology, Vol. 130, Issue 1, pp. e103, (2020) (PubMed).

Ganesan, Ahmed, Okoye, Arutyunova, Babu, Turnbull, Kundu, Shields, Agopsowicz, Xu, Tabana, Srivastava, Zhang, Moon, Belovodskiy, Hena, Kandadai, Hosseini, Hitt, Walker, Smylie, West, Siraki, Lemieux et al.: "Comprehensive in vitro characterization of PD-L1 small molecule inhibitors. ..." in: Scientific reports, Vol. 9, Issue 1, pp. 12392, (2019) (PubMed).

Chen, Xu, Du, Hou, Fan, Wu, Yan: "Enhanced Expression of PD-L1 on Microglia After Surgical Brain Injury Exerts Self-Protection from Inflammation and Promotes Neurological Repair." in: Neurochemical research, Vol. 44, Issue 11, pp. 2470-2481, (2019) (PubMed).

Son, Park, Seo, Lee, Heo, Kim: "A small-sized protein binder specific for human PD-1 effectively suppresses the tumour growth in tumour mouse model." in: Journal of drug targeting, pp. 1-9, (2019) (PubMed).

Aliases for PD-L1 Proteins

CD274 molecule (CD274) Proteins
CD274 antigen (Cd274) Proteins
programmed cell death 1 ligand 2 (PDCD1LG2) Proteins
CD274 molecule (Cd274) Proteins
A530045L16Rik Proteins
B7-H Proteins
B7H1 Proteins
B7h1 Proteins
PD-L1 Proteins
PDCD1L1 Proteins
Pdcd1l1 Proteins
PDCD1LG1 Proteins
Pdcd1lg1 Proteins
PDL1 Proteins
Pdl1 Proteins
RGD1566211 Proteins
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