NK3 Homeobox 1 (NKX3-1) (Middle Region) Peptide
NKX3-1
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all NKX3-1 products
- NKX3-1 (NK3 Homeobox 1 (NKX3-1))
- Protein Region
- Middle Region
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TPTEPESDAH FETYLLDCEH NPGDLASAPQ VTKQPQKRSR AAFSHTQVIE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Nkx3-1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NKX3-1 (NK3 Homeobox 1 (NKX3-1))
- Synonyms
- Xbagpipe Peptide, Xbap Peptide, bagpipe Peptide, koza Peptide, nkx3-1 Peptide, nkx3.1 Peptide, si:ch211-67o1.2 Peptide, nkx3a Peptide, MGC53041 Peptide, MGC97890 Peptide, Bax Peptide, NKX3.1 Peptide, NKX3A Peptide, Nkx-3.1 Peptide, BAPX2 Peptide, NKX3 Peptide, NK3 homeobox 1 L homeolog Peptide, NK3 homeobox 1 Peptide, NK-3 transcription factor, locus 1 (Drosophila) Peptide, nkx3-1.L Peptide, NKX3-1 Peptide, nkx3-1 Peptide, Nkx3-1 Peptide
- Background
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Nkx3-1 is a transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. It plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Nkx3-1 acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells and plays a role in the formation of minor salivary glands (particularly palatine and lingual glands). It is essential for appropriate differentiation and secretory function of the bulbourethral gland.
Alias Symbols: Bax, NKX3.1, NKX3A, Nkx-3.1, bagpipe
Protein Size: 237 - Molecular Weight
- 27 kDa
- Gene ID
- 18095
- NCBI Accession
- NM_010921, NP_035051
- UniProt
- P97436
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