Barrier To Autointegration Factor 1 (BANF1) (Middle Region) Peptide
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- Target See all BANF1 products
- BANF1 (Barrier To Autointegration Factor 1 (BANF1))
- Protein Region
- Middle Region
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- FDKAYVVLGQ FLVLKKDEDL FREWLKDTCG ANAKQSRDCF GCLREWCDAF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-BANF1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- BANF1 (Barrier To Autointegration Factor 1 (BANF1))
- Synonyms
- BAF Peptide, BCRP1 Peptide, D14S1460 Peptide, NGPS Peptide, Baf Peptide, Bcrp1 Peptide, L2bp1 Peptide, L2bp1/Baf Peptide, BANF1 Peptide, DKFZp468C097 Peptide, C78287 Peptide, baf Peptide, bcrp1 Peptide, fa01c01 Peptide, wu:fa01c01 Peptide, zgc:77767 Peptide, CG7380 Peptide, Dmel\\CG7380 Peptide, anon-WO0172774.178 Peptide, dBAF Peptide, banf1 Peptide, banf1-a Peptide, banf1-b Peptide, barrier to autointegration factor 1 Peptide, barrier to autointegration factor 1 pseudogene Peptide, barrier to autointegration factor Peptide, barrier to autointegration factor 1 S homeolog Peptide, BANF1 Peptide, Banf1 Peptide, banf1 Peptide, LOC100397017 Peptide, baf Peptide, banf1.S Peptide
- Background
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The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.
Alias Symbols: BAF, BCRP1, D14S1460, MGC111161
Protein Size: 89 - Molecular Weight
- 10 kDa
- Gene ID
- 8815
- NCBI Accession
- NM_003860, NP_003851
- UniProt
- O75531
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