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Inturned Planar Cell Polarity Effector Homolog (INTU) (C-Term) Peptide

INTU Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN1541686
  • Target See all INTU products
    INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))
    Protein Region
    C-Term
    Origin
    Human
    Source
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    TLEEVAQLSG SIHPQLIKNF HQCCLSIRAV FQQTLVEEKK KGLNSGDHSD
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-INTU Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))
    Synonyms
    9230116I04Rik Peptide, 9430087H23Rik Peptide, Pdzd6 Peptide, Pdzk6 Peptide, mKIAA1284 Peptide, INT Peptide, PDZD6 Peptide, PDZK6 Peptide, Xint Peptide, in Peptide, int Peptide, pdzd6 Peptide, inturned planar cell polarity protein Peptide, inturned planar cell polarity protein S homeolog Peptide, Intu Peptide, INTU Peptide, intu Peptide, intu.S Peptide
    Background
    INTU plays a key role in ciliogenesis and embryonic development. INTU is a regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. It plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension and has an indirect effect on hedgehog signaling.

    Alias Symbols: FLJ41326, INT, KIAA1284, PDZD6, PDZK6

    Protein Size: 942
    Molecular Weight
    104 kDa
    Gene ID
    27152
    NCBI Accession
    NM_015693, NP_056508
    UniProt
    Q9ULD6
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