Inturned Planar Cell Polarity Effector Homolog (INTU) (C-Term) Peptide
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- Target See all INTU products
- INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))
- Protein Region
- C-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TLEEVAQLSG SIHPQLIKNF HQCCLSIRAV FQQTLVEEKK KGLNSGDHSD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-INTU Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))
- Synonyms
- 9230116I04Rik Peptide, 9430087H23Rik Peptide, Pdzd6 Peptide, Pdzk6 Peptide, mKIAA1284 Peptide, INT Peptide, PDZD6 Peptide, PDZK6 Peptide, Xint Peptide, in Peptide, int Peptide, pdzd6 Peptide, inturned planar cell polarity protein Peptide, inturned planar cell polarity protein S homeolog Peptide, Intu Peptide, INTU Peptide, intu Peptide, intu.S Peptide
- Background
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INTU plays a key role in ciliogenesis and embryonic development. INTU is a regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. It plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension and has an indirect effect on hedgehog signaling.
Alias Symbols: FLJ41326, INT, KIAA1284, PDZD6, PDZK6
Protein Size: 942 - Molecular Weight
- 104 kDa
- Gene ID
- 27152
- NCBI Accession
- NM_015693, NP_056508
- UniProt
- Q9ULD6
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