Asparagine-Linked Glycosylation 10, alpha-1,2-Glucosyltransferase Homolog (ALG10) (N-Term) Peptide
ALG10
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ALG10 products
- ALG10 (Asparagine-Linked Glycosylation 10, alpha-1,2-Glucosyltransferase Homolog (ALG10))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SVGNFYLLYL LFHKVQPRNK AASSIQRVLS TLTLAVFPTL YFFNFLYYTE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ALG10B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ALG10 (Asparagine-Linked Glycosylation 10, alpha-1,2-Glucosyltransferase Homolog (ALG10))
- Synonyms
- ALG10 Peptide, KCR1 Peptide, ALG10A Peptide, DIE2 Peptide, Alg10 Peptide, ALG10B Peptide, Alg10b Peptide, ALG10B, alpha-1,2-glucosyltransferase Peptide, ALG10, alpha-1,2-glucosyltransferase Peptide, dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase Peptide, ALG10B Peptide, ALG10 Peptide, LOC100727296 Peptide, Alg10 Peptide, LOC100064952 Peptide
- Background
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ALG10B is a putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. ALG10B transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc(2)-PP-Dol. When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2.
Alias Symbols: ALG10, KCR1
Protein Size: 473 - Molecular Weight
- 55 kDa
- Gene ID
- 144245
- NCBI Accession
- NM_001013620, NP_001013642
- UniProt
- Q5I7T1
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