Deltex Homolog 4 (Drosophila) (DTX4) (C-Term) Peptide
DTX4
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Deltex Homolog 4 (DTX4) products
- Deltex Homolog 4 (DTX4) (Deltex Homolog 4 (Drosophila) (DTX4))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LPVCLTRPPK LVLHPPPVSK SEIKSIPGVS NTSRKTTKKQ AKKGKTPEEV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DTX4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Deltex Homolog 4 (DTX4) (Deltex Homolog 4 (Drosophila) (DTX4))
- Synonyms
- RNF155 Peptide, AI449438 Peptide, BC044798 Peptide, D930042H13 Peptide, zgc:163052 Peptide, LRRGT00037 Peptide, deltex E3 ubiquitin ligase 4 Peptide, deltex 4, E3 ubiquitin ligase Peptide, DTX4 Peptide, Dtx4 Peptide, dtx4 Peptide
- Background
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DTX4 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. It functions as an ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
Alias Symbols: RNF155
Protein Size: 619 - Molecular Weight
- 67 kDa
- Gene ID
- 23220
- NCBI Accession
- NM_015177, NP_055992
- UniProt
- Q9Y2E6
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