Activating Transcription Factor 1 (AFT1) (N-Term) Peptide
AFT1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all AFT1 products
- AFT1 (Activating Transcription Factor 1 (AFT1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DLSSEDTRGR KGDGENSGVS AAVTSMSVPT PIYQTSSGQY IAIAPNGALQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ATF1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AFT1 (Activating Transcription Factor 1 (AFT1))
- Synonyms
- ews-atf1 Peptide, fus/atf-1 Peptide, treb36 Peptide, ATF1 Peptide, EWS-ATF1 Peptide, FUS/ATF-1 Peptide, TREB36 Peptide, Atf-1 Peptide, wu:fc92c07 Peptide, zgc:64099 Peptide, activating transcription factor 1 Peptide, activating transcription factor 1 L homeolog Peptide, atf1 Peptide, ATF1 Peptide, MGC85066 Peptide, atf1.L Peptide, Atf1 Peptide
- Background
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ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT [AC] [AG]-3'), a sequence present in many viral and cellular promoters. ATF1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes.
Alias Symbols: EWS-ATF1, FUS/ATF-1, TREB36
Protein Size: 271 - Molecular Weight
- 29 kDa
- Gene ID
- 466
- NCBI Accession
- NM_005171, NP_005162
- UniProt
- P18846
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