Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2) (C-Term) Peptide
MARCH2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MARCH2 products
- MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- IALFTIYVLW TLVSFRYHCQ LYSEWRKTNQ KVRLKIREAD SPEGPQHSPL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MARCH2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))
- Synonyms
- MARCH-II Peptide, RNF172 Peptide, rgd1306395 Peptide, marh2 Peptide, RGD1306395 Peptide, 9530046H09Rik Peptide, membrane associated ring-CH-type finger 2 Peptide, membrane associated ring-CH-type finger 2 S homeolog Peptide, E3 ubiquitin-protein ligase MARCH2 Peptide, membrane-associated ring finger (C3HC4) 2 Peptide, MARCH2 Peptide, march2.S Peptide, march2 Peptide, Tsp_09446 Peptide, marh2 Peptide, March2 Peptide
- Background
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MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking.
Alias Symbols: MARCH-II, RNF172
Protein Size: 246 - Molecular Weight
- 27 kDa
- Gene ID
- 51257
- NCBI Accession
- NM_016496, NP_057580
- UniProt
- Q9P0N8
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